The chemical reasons rely on the fact that cystine is a much better homolog of cystathionine than is cysteine for binding at the active site of CGL (c.f.the structure of cystathionine with the structure of cystine in Fig.1), and the nature of the leaving groups for reactions1and2. The ...
cysteine.241,244In the proposed catalytic mechanism, the internal aldimine reacts with cystine to form the external aldimine via a gem-diamine.242The most probable candidate to deprotonate the substrate amino group fornucleophilicattack of the internal aldimine is His114. In the presence of ...
(C) l-Cystine (14) formation by OvoA in the presence of 1. (D) Proposed catalytic mechanism of OvoA to produce 2 or 13. OvoA catalyzes the oxidative coupling between 1 and 12 to generate the 5-histidylcysteine sulfoxide conjugate (13), which is the precursor of the final product 11...
Cystine lyase degrades l-cystine by a beta-elimination to form cysteine persulfide, pyruvate, and ammonia. This enzyme is common in Brassica sp. and has be... Hamamoto,Mazelis - 《Plant Physiology》 被引量: 161发表: 1986年 Crystal structure of the cystine C-S lyase from Synechocystis: Sta...
Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition. elife. 2017;6 https://doi.org/10.7554/eLife.27713. Shin C-S, Mishra P, Watrous JD, Carelli V, D’Aurelio M, Jain M, Chan DC. The glutamate/cystine xCT antiporter antagonizes glutamine ...
Control; #p < 0.01 for MPP+ vs. MPP+ + Catalase by post-hoc ANOVA. Full size image MS analysis of parkin oxidation It is most important to link structure with function, that is, to identify the critical residues in parkin whose oxidative state regulates the E3 ligase activity. Previous ...
Cysteine was either incubated with 113.5 µM H2O2, 200 µM NO2−, or 350 µM NO3−at the lowest observed pH (5.8) or by a combination of all three. Treatment with H2O2alone or in the combination showed little effect except a slightly increased cystine level. Addition of ...
THE PRIMARY STRUCTURE OF Escherichia coli GLUTAREDOXIN DISTANT HOMOLOGY WITH THIOREDOXINS IN A SUPERFAMILY OF SMALL PROTEINS WITH A REDOX‐ACTIVE CYSTINE DISULFIDE/CYSTEINE DITHIOLdoi:10.1111/j.1432-1033.1983.tb07731.xJan-OlovHöögHansJörnvall...
cystine copper complexIn this work the covalent anchoring of C-protected Cu(II)– l-cysteine and Cu(II)– l-cystine complexes onto a surface-modified silica gel is described. Conditions of the syntheses were varied and the obtained structures were studied by classical analytical (titration) as ...
L-Cysteine andL-cysteine intercalated MgAl-LDHs have been prepared by coprecipitation. It was found thatL-cysteine is oxidized toL-cystine by some oxidants (e.g., H2O2), just as in solution, whereas the intercalatedL-cysteinewas oxidized by Br2to the single product of cysteic acid, irrespecti...