CKD-EPI评估方程CystatinC评估方程肾小球滤过率(glomerularfiltrationrate,GFR)是评价肾脏功能最重要的指标之一.2006年,中华医学会肾脏病学分会推荐两个方程式计算GFR.其中,公式2(c—cGFR2)中引入了半胱氨酸蛋白酶抑制剂C(CystatinC,CysC)作为变量,公式1(c—cGFR1)以CysC作为单独变量.而且,已有学者的研究表明蒋玲琳南京医科大学附属南...
CKD.EPI基于CystatinC开发的GFR评估方程,来指导临床选择更合适的GFR评 估方法。 研究目的 以双血浆法‰Tc—DTPA血浆清除率定的GFR为参考标准,评价体表面积标准 化的Cockcrofi.Gault方程、简化MDRD方程、改良后的简化MDRD方程,肾动态 显像法(Gates法)及以Cystatin ...
摘要 肾小球滤过率(glomerularfiltrationrate,GFR)是评价肾脏功能最重要的指标之一。2006年,中华医学会肾脏病学分会推荐两个方程式计算GFR。其中,公式2(c—cGFR2)中引入了半胱氨酸蛋白酶抑制...展开更多 作者 蒋玲琳 杜新 机构地区 南京医科大学附属南京医院(南京市第一医院)肾内科 出处 《华南国防医学杂志》...
摘要:目的探讨基于血清cystatinc、crea的CKD-EPI公式及相关的肾脏功能标志物在评价肾脏功能、诊断肾脏疾病和衡量肾病进程中的临床应用价值。方法采用增强透射免疫比浊法测定血清胱氨酸蛋白酶抑制剂C(cystatinc,cyc),酶法测定血清肌酐(crea)、免疫比浊法测定血清β2微球蛋白(β2-mg);应用CKD-EPI公式估算肾小球滤过率...
Equation: eGFR using the CKD-EPI Creatinine-Cystatin C Equation (2021). eGFRcr-cys= 135 x min(Scr/к, 1)αx max(Scr/к, 1)-0.544x min(Scys/0.8, 1)-0.323x max(Scys/0.8, 1)-0.778x 0.9961Agex 0.963 [if female] where:
SerumCystatin C (mg/L) NOTE: CKD-EPI GFR is only valid with serum creatinine methods are traceable to IDMS Ageyears RaceAfrican AmericanAll other races* GenderMaleFemale alb/crACRmg/grams TRACEABLE TO IDMS(What is this?)NoYes EQUATION:VALUE: ...
1). Cystatin C had the highest AUC for outcome prediction (0.630; 95% confidence interval [CI]: 0.556 to 0.704; P < 0.001), followed by 2021 CKD-EPI eGFRcr-cys (AUC: 0.625; 95% CI: 0.551 to 0.699) (Table S1). Fig. 1 Receiver operator curves for parameters and eGFR derived ...
Simple cystatin C formula compared to sophisticated creatinine and cystatin C-based formulas (CKD-EPI) for estimation of glomerular filtration rateR., HojsS., BevcR., EkartM., GorenjakL., Puklavec
Figure2shows the forest plots of mean P10-P15 accuracies. The Tan equation had the highest mean P10-P15 accuracy (35.2%), while the Perkins equation had the lowest (14.6%). The mean P20 accuracy of CKD-EPI equations was around 77%, whether with cystatin C alone or combined with creatin...
The eGFR is calculated using cystatin C measurements calibrated to International Federation of Clinical Chemistry (IFCC) certified reference material, along with the patient's age and sex, according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI 2012) equat...