* Dose reduction is recommended for all doses, both before and after tooth extraction. 1.36 to 2.83(120 to 250 micromol/L) 10 mg/kg twice daily 2.83 to 5.66 (250 to 500 micromol/L) 10 mg/kg daily >5.66 (>500 micromol/L) 10 mg/kg every 48 hoursor5 mg/kg every 24 hours 3...
Studies in man have demonstrated that after intravenous administration of a single dose of 10–15 mg of tranexamic acid/kg body weight, the plasma concentration curve shows three monoexponential decays: the first is a very rapid one, the second has a half-life of 1.3–2.0 hours and the ...