CyclophosphamidePage1Cyclophosphamide(Cytoxan)DescriptionCyclophosphamide(Cytoxan)belongstoaclassofdrugsknownasalkylatingagents,whichhavebeenusedtotreatsometypesofcancer.Itisalsoconsideredanimmunosuppressant—amedicinethatcandecreasetheimmuneresponse.FastFactsCyclophosphamideisreservedforsevere,refractoryrheumatoidarthritisorsevere...
BCS Class1,3 StabilityStable, but light sensitive. Incompatible with oxidizing agents. CAS DataBase Reference50-18-0(CAS DataBase Reference) NCI Dictionary of Cancer Termscyclophosphamide FDA UNII6UXW23996M NCI Drug Dictionarycyclophosphamide
It shows that the O6-Methylguanine accumulation in cancer patients receiving Cyclophosphamide is very likely to occur and the analysis method proposed by Vianney, Harahap, & Suryadi (2021) is potential to be used for Therapeutic Drug Monitoring in this group of patients.doi:10.1016/j.heliyon.2021...
Cytotoxic Drug Treatment Eva D. Papadimitraki MD, Dimitrios T. Boumpas MD, FACP, in Systemic Lupus Erythematosus, 2007 Bladder Toxicity Including Bladder Carcinoma The appearance of hemorrhagic cystitis and bladder carcinoma has been well documented in patients receiving long-term oral CY.24 The rol...
exhaust scrubbing system/ of the biohazard cabinet must be replaced whenever they restrict required airflow velocity or if they are overtly contaminated (eg, by a breach in technique that causes hazardous drug to be introduced onto the clean side of the supply high efficiency particulate air ...
Chemotherapy: Cyclophosphamide monohydrate is primarily used as an anticancer drug in chemotherapy. Its purpose in this field is to inhibit the growth of cancer cells by interfering with their DNA replication and cell division. The mechanism of action of Cyclophosphamide monohydrate involves the formation...
Impaired CD8 T cell responses after CY treatment CY is a cytotoxic and lymphodepleting drug. A single dose of CY (150 mg/kg) resulted in a 75% reduction of splenic cellularity [18] as well as of total CD8 T cell numbers (data not shown) Thus, expansion of anti-tumor CD8 T cells ...
The article presents a case study of a 47-year-old woman who has died due to neutropenia and multiple organ dysfunction syndromes (MODS) during chemotherapy with cyclophosphamide, docetaxel & pirarubicin as effect of drug on route & reac... None - 《Reactions Weekly》 被引量: 0发表: 2016年...
Kaplan–Meier plot of PFS (a), OS (b), and response rates (c).αBest responses were attained in induction among patients who had received at least one dose of the study drug.βResponses among patients who had completed induction and autologous stem cell transplant.δResponses among patients ...
With its many chemotherapy drugs such as 5 -FU , such as cyclophosphamide may enhance the joint use of organisms, therefore, more tumor sugar can be used as an ideal anti-tumor drug to be developed and used. 翻译结果5复制译文编辑译文朗读译文返回顶部 ...