Thus, the nitrone 186 (Equation 122) undergoes cyclization in nonpolar aprotic solvents such as benzene or toluene and polar aprotic solvents such as DMSO, DMF, or acetonitrile to afford the five-membered ring
Those preferably utilizable are hydrocarbons, such as toluene and xylene, furthermore ethers, such as dibutyl ether, tetrahydrofuran, dioxane, glycol dimethyl ether and diglycol dimethyl ether, additionally polar solvents, such as dimethyl sulphoxide, sulpholane, dimethylformamide and N-methyl-...
The IAHB remains in the ACPD when it is dissolved in a nonpolar solvents such as CCl 4 or cyclohexane, or when a weak proton acceptor such as CH 3 CN or dioxane is present; in polar basic-type solvents (pyridine, isoquinoline, triethylamine), the enol proton dissociates, forming an ...
The kinetic data revealed that the reactions in nonpolar benzene or slightly polar CH 2 Cl 2 proceeded in two steps, each following a common S N 2 mechanism. In the first step, Mel attacked the platina(II)cyclopentane center rather than the dimethyl-platinum(II) center, because the first ...