环苯扎林在2.5 mg至10 mg的剂量范围内表现出线性药代动力学, 并经历肝肠循环。它与血浆蛋白高度结合。每天给药3次后,药物会积聚,在3至4天内达到稳态,血浆浓度约为单次给药后的四倍。 在健康受试者接受10 mg tid(n = 18)的稳态下,血浆峰值浓度为25.9 ng / mL(范围为12.8至46.1 ng / mL), 并且在8...
Common Generic Name(s):cyclobenzaprine, cyclobenzaprine HCl, cyclobenzaprine hydrochloride Pronunciation:SYE-kloe-BEN-za-preen Drug Classes:muscle relaxant Availability:prescription only, generic available How is it used?capsule that is swallowed, tablet that is swallowed ...
Your condition will not improve any faster, and your risk of side effects will increase. Muscle Spasm Immediate-release tablet Adult: 5 mg orally every 8 hours, may increase the dose to 7.5-10 mg orally every 8 hours as needed Under 15 years of age: Safety and efficacy not established ...
Adult: 5 mg orally every 8 hours, may increase the dose to 7.5-10 mg orally every 8 hours as needed Under 15 years of age: Safety and efficacy not established Over 15 years of age: 5 mg orally every 8 hours, may increase the dose to 7.5 mg orally every 8 hours as needed ...
10. Bianchi M. Evaluation of cyclobenzaprine for skeletal muscle spasm of local origin. In: Clinical Evaluation of Flexeril (Cyclobenzaprine HCl/MSD). Minneapolis, MN: Postgraduate Medicine Communications; 1978:25-29. 11. Brown BR Jr, Womble J. Cyclobenzaprine in intractable pain syndromes with mu...
CYCLOBENZAPRINE HCL 1.2 Synonyms [3-(5-H-Dibenzo[a,d]cyclohepten-5-ylidene)propyl]dimethylamine; 10,11-dehydroamitriptyline; 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-; 3-(5h-dibenzo(a,d)cyclohepten-5-ylidene)-n,n-dimethyl-1-propanamin; 3-(5H-Dibenzo[...
Cyclobenzaprine hydrochloride, USP is a white, crystalline tricyclic amine salt with the molecular formula C20H21N·HCl and a molecular weight of 311.9. It has a melting point of 217°C, and a pKa of 8.47 at 25°C. It is freely soluble in water and alcohol, sparingly soluble in isopropan...
Cyclobenzaprine - Uses, Side Effects, and More Medically Reviewed by Beth Johnston, PharmD, BCPS on Oct 06, 2024 | Written by M. Sruthi, MBBS Common Brand Name(s): Amrix, Fexmid, Flexeril Common Generic Name(s): cyclobenzaprine, cyclobenzaprine HCl, cyclobenzaprine hydrochloride Pronunciation...