Prior to initial dose of study drug administration, and during the hours, days, and weeks after participants will receive serial longitudinal assessments of psychological and somatic symptoms, neurocognitive function, and adverse events. 显示全部
Cyclobenzaprine is not new to medicine, having been first synthesized almost 50 years ago. Experimental studies revealed that the drug had skeletal muscle relaxant effects; controlled trials confirmed its efficacy for relieving the signs and symptoms of acute muscle spasm of local origin. In 1977, ...
Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.Brand Name Synonyms Amrix Flexeril Generic Drug Synonyms and Salts...
During the acute recovery phase of myocardial infarction and in patients with irregular heartbeat, heart block or conduction disturbances, or congestive heart failure Do not use simultaneously or within 14 days of discontinuing antidepressants Hyperpyretic crisis seizures and deaths have occurred in patien...
During the acute recovery phase ofmyocardial infarctionand in patients with irregular heartbeat,heart blockor conduction disturbances, orcongestive heart failure Do not use simultaneously or within 14 days of discontinuingantidepressants Hyperpyretic crisis seizures and deaths have occurred in patients receivi...
This article presents a case study involving patients who developed serotonin syndrome during concomitant treatment with cyclobenzaprine while receiving phenelzine or duloxetine. One patient underwent resection of an infected hip arthroplasty. On postoperative day 6, the patient started receiving oral ...
In one case of accidental overdose, the victim developed severe hypothermia and then developed cardiac arrest during transport. ANIMAL STUDIES: Ptyalism, emesis, tremors, convulsions and increased respiratory rate developed and death occurred within 1 hour following single oral doses of 180 mg/kg or...
Substantial amounts of this benzodiazepine may pass into breast milk. Therefore, it should not be used by nursing mothers as it may be harmful to the infant. Additionally, it may be harmful to a developing baby, hence, this benzodiazepine should be avoided during pregnancy unless considered esse...
This benzodiazepine is not safe to use while breastfeeding because taking it while nursing can cause harmful side effects to the nursing infant. More importantly, this medication may cause birth defects, especially if taken during the first trimester of pregnancy. ...
and have revealed no evidence of impaired fertility or harm to the fetus due to Cyclobenzaprine. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy...