Always follow your doctor's dosing instructions. Continue reading How long does it take for Flexeril to work? Flexeril (cyclobenzaprine) is a fast-acting medicine and you should start to feel some muscle relaxant effects within 30 minutes to one hour. The full effect can take up to 7 days...
The oral bioavailability of cyclobenzaprine has been estimated to be between 0.33 and 0.55. Cmaxis between 5-35 ng/mL and is achieved after 4 hours (Tmax). AUC over an 8 hour dosing interval was reported to be approximately 177 ng.hr/mL.|After administration of a radio-labeled dose of ...
Although there were no notable differences in Cmax or Tmax, cyclobenzaprine plasma AUC is increased by 40% and the plasma half-life of cyclobenzaprine is prolonged in elderly subjects greater than 65 years of age (50 hours) after dosing with cyclobenzaprine hydrochloride extended-release capsules com...
Less frequent dosing should be considered for hepatically impaired or elderly patients (see PRECAUTIONS, Impaired Hepatic Function, and Use in the Elderly). HOW SUPPLIED Cyclobenzaprine hydrochloride, USP 5 mg tablets are supplied as butterscotch yellow colored film-coated capsule shaped convex tablets,...