在健康受试者接受10 mg tid(n = 18)的稳态下,血浆峰值浓度为25.9 ng / mL(范围为12.8至46.1 ng / mL), 并且在8小时内的浓度时间(AUC)曲线下的面积给药间隔为177 ng.hr/mL(范围为80到319 ng.hr/mL)。 环苯扎林被广泛代谢,主要以葡萄糖苷酸的形式经肾脏排泄。细胞色素P-450 3A4、1A2和2D6(在较小...
5 mg, 7.5 mg, 10 mg oral tablets 15 mg, 30 mg extended-release oral capsules How should I store cyclobenzaprine? Cyclobenzaprine should be stored at roomtemperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C),...
Comparison of the single-dose pharmacokinetics of once-daily cyclobenzaprine extended-release 30 mg and cyclobenzaprine immediate-release 10 mg three times... The clinical utility of cyclobenzaprine for the treatment of muscle spasm associated with acute, painful musculoskeletal conditions is limited by ch...