产品名称:Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 ELISA Kit 检测范围:1.56-100 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 标本要求 1.标本采集后尽早进行提取,提取按相关文献进行,提取后应尽快进行实验。若不能马上进行试验,可...
The role of cyclins, cyclin dependent kinase (CDK) and cyclin kinase inhibitor (CKI) have been founded. 发现并确立了细胞周期蛋白(Cyclin)、细胞周期蛋白依赖激酶(CDK)和细胞周期蛋白依赖性激酶抑制因子(CKI)在真核生物细胞周期调控中的作用。3
a covalent inhibitor of cyclin-dependent kinase 7(CDK7),which demonstrated promising anti-tumor activity against different cancer types.By introducing the anti-tumor behaviors and the potential targets for different cancers,this review aims to provide more effective approaches to CDK7 inhibitor-based ...
The p27GST-fusion protein of the point mutation that replaces phenylalanine at residue 64 to alanine (F64A) showed approximately twofold less inhibition of cdk2 kinase activity. The cellular response to the introduction of the F64A mutant form of p27was compared to that of p27wild type by...
中文名称:Recombinant Human Cyclin-Dependent Kinase Inhibitor 1B/CDKN1B Protein(N-6His)英文名称:Recombinant Human Cyclin-Dependent Kinase Inhibitor 1B/CDKN1B Protein(N-6His) 品牌:沪震生物产地:中国/上海 保存条件:-20°C纯度规格:> 99% 产品类别:重组蛋白 ...
cyclin-dependent kinase inhibitor/-s ctDNA: circulating tumor DNA EGFR: epithelial growth factor receptor ER: estrogen receptor GBM: glioblastoma multiforme HNSCC: head and neck squamous cell carcinoma HPV: human papillomavirus HR: homologous recombination ...
By RT-PCR,the likely gene of cyclin-dependent kinase inhibitor in Oryza sativa(9311) was cloned and named OsICK1. 细胞周期蛋白依赖性激酶抑制剂(ICK)是一种能够影响细胞生长和发育的重要调控蛋白。 更多例句>> 3) cyclin-dependent-kinase inhibitor 细胞周期依赖性蛋白激酶抑制剂4...
而实现对细胞周期不同时相的推进和转化作用.CDK的活性依赖于其正调节亚基cyclin的顺序性表达和其负调节亚基CDI(cyclin dependent kinase inhibitor,CDK抑制因子)的浓度.同时,CDK的活性还受到磷酸化和去磷酸和,以及癌基因和抑癌基因的调节.在哺乳动物中至少存在9种CDK,即CDK1—9,CDK家族蛋白含有一段类似的CDK结构域,...
There are crystal structures of PCNA bound to PIP-box peptides from six different proteins: the cyclin-dependent kinase inhibitor 1 (CDKN1A, also known asp21WAF1/CIP1, and hereafter referred to as p21) (Gulbis, et al., 1996),FEN1(Bruning & Shamoo, 2004), the subunit 3 of the human...
a gene encoding for cyclin-dependent kinase inhibitor p18(INK4c) (p18), as the top candidate gene for inducing the Slec2c1-associated expansion of B1a cells. A novel single nucleotide polymorphism in the NZB allele of the Cdkn2c promoter is associated with a significantly reduced Cdkn2c expr...