Cyclin-Dependent Kinase 1 Cyclin D1 Cell Cycle M Phase Cancer Cell Phosphotransferase Mouse View all Topics Featured Authors Hu, Weiwei College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China Citations 4,349 h-index 37 Publications 36 Meng, Xianggao Jgao Central China Normal Unive...
Chuang JY, Wang SA, Yang WB, Yang HC, Hung CY, Su TP, Chang WC, Hung JJ (2012) Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA- binding activity during mitosis in cancer cells. OncogeneChuang, J. Y., S. A. Wang, W. B. Yang, H. C. Yang, C. ...
细胞周期蛋白(cyclin)和周期蛋白依赖性激酶(cyclin-dependent kinases,CDK)是调控细胞周期的关键因子。尽管CDK家族包含将近20个成员,其激活因子也有29个,但不同的细胞周期仅受控于5对特定的组合模式:cyclin D -CDK4/6 调控DNA合成前期(G1 phase), cyclin...
在有丝分裂结束后,Cyclin B的降解是终止有丝分裂过程的关键步骤。细胞通过把Cyclin B-CDK复合物暴露在泛素化酶系统中,使Cyclin B得以降解。 Cyclin C 与其他细胞周期蛋白相比,Cyclin C的研究相对较少,但已被发现在细胞周期中发挥重要的功能。它与CDK8(Cyclin-dependent kinase 8)结合成一个复合物,被称为Mediator...
二、CDK5 与 cyclin B 基本特性 (一)CDK5 结构与特性 CDK5,即周期蛋白依赖性激酶 5(Cyclin-Dependent Kinase 5),隶属于脯氨酸引导的丝氨酸 / 苏氨酸激酶家族。该激酶最早从牛脑提取物中成功分离,其结构与细胞分裂周期蛋白 2(CDC2)以及周期蛋白依赖性激酶 2(CDK2)呈现出较高的同源性,经序列比对分析,与 CDC2 ...
With the activation of the cyclin-dependent kinase 1 (CDK1)–cyclin B1 complex at mitotic entry1,2,3, cells isochronally undergo a series of morphological events, which commence with the disassembly and shrinkage of FAs that enable the retraction of the cell margins and the formation of ...
21 reagents referenced in Cyclin-dependent kinase 1-dependent phosphorylation of cAMP response element-binding protein decreases chromatin occupancy.
表1:细胞周期各阶段及其特点 细胞周期标记物 细胞周期的关键蛋白主要有:细胞周期蛋白Cyclin,周期蛋白依赖性激酶CDKs(cyclin-dependent kinases),CDK抑制因子CKIs(cyclin-dependent kinase inhibitors)和CDK激活激酶CAK(CDK-activating kinase),它们在不同时期发挥各自重要的作用: ...
Definition Cyclin-dependent kinase inhibitor 1B (CDKNB1B) is also known as p27 and Kip1; Cip/Kip family [ CIP/KIP family ].DefinitionCyclin-dependent kinase inhibitor 1B (CDKNB1B) is also known as p27 and Kip1; Cip/Kip family [ CIP/KIP family ].CIP/KIP familyCIP/KIP family...
英文名称:Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody,中文名称:细胞周期蛋白依赖性激酶抑制剂1B(CDKN1B)抗体,产品货号:Catalogue No: abx328276,<div><p>CDKN1B抗体是一种抗CDKN1B的兔多克隆抗体。<p>靶CDKN1B<p>人、小鼠、大鼠<p>宿主兔<p>克隆