B. 免疫印记(WB)分析特征蛋白 a) G1/S arrest:2mM胸腺嘧啶处理24h的HeLa细胞,细胞周期蛋白D1(Cyclin D1)、Cyclin B1、Cyclin B2和叉头框蛋白M1(FOXM1)上调。 图9 Cyclin D1抗体(26939-1-AP,A)和FOXM1抗体(13147-1-AP,B)检测处理前后Hela b) G2/M arrest:100ng/mL诺考达唑处理18h的HeLa细胞,Cyclin...
At the end of mitosis, cyclin B1 is targeted for degradation by the anaphase-promoting complex (APC), allowing for cell cycle progression (11). Research studies have shown that cyclin B1 is overexpressed in breast, prostate, and non-small cell lung cancers (12-14). Lorca, T. ...
Cyclin B1 Blocking Peptide 供应商 Fitzgerald 产品货号 33R-1305 产品报价 ￥询价/100ug 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。 产品新闻 背景资料 Cell Cycle & Cell Death ...
Cell cycleCyclinB1USP14Breast cancer is the most common malignant tumor among women in China, which seriously threatens women's physical and mental health. Tumorigenesis is closely related to the dysregulation of cell cycle. The cell cycle progression includes interphase and mitotic phase (M phase)...
Cyclin B1 (CCNB1) is a regulatory protein involved in mitosis. CCNB1 creates a complex with p34(cdc2) to form the maturation-promoting factor (MPF). CCNB1 is vital for the control of the cell cycle at the G2/M (mitosis) transition. CCNB1 builds up steadily during the G2 and is imm...
Cyclin B1, also known as Ccnb1 and Ccnb is a protein of 433 amino acids and 48 kD. The human CCNB1 or CCNB gene locus maps to 5q12 and the mouse ccnb1 gene locus to chromosome 13 (56.00 cM). Cyclin B1 is essential for the control of the cell cycle at the G2/M (mitosis) tra...
Cyclin B1在肿瘤发生发展过程中起作用。 Cyclin B1过表达能促进G /M期转换,甚至导致细胞 一、 Cyclin B1与细胞周期调控 增生失控以及恶性转化 ;过表达转录因子c—Myb Cyclin B1是在有丝分裂过程中起调控作用的周 能够刺激Cyclin B1表达,进而促进G /M期转换 ; 期蛋白,它作为调节亚基参与MPF活化调节,进而参 Yuan ...
[15] Han SJ, Martins J, Yang Y, et al. The translation of Cyclin B1 and B2 is differentially regulated during mouse oocyte reentry into the meiotic cell cycle[J]. Sci Rep, 2017, 7(1): 14077. DOI: 10.1038/s4...
Cyclin B1 Rabbit Monoclonal Antibody -20℃保存,Western一抗稀释液-20℃或4℃保存,一年有效。Western一抗稀释液优先推荐4℃保存,长期不使用可以考虑-20℃保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。 注意事项: 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验,请注意回收使用...
Primate-specific RFPL1 gene controls cell-cycle progression through cyclin B1/Cdc2 degradation. Cell Death Differ. 18, 293-303.Bonnefont J, Laforge T, Plastre O, Beck B, Sorce S, Dehay C, Krause KH. Primate-specific RFPL1 gene controls cell- cycle progression through cyclin B1/Cdc2 ...