Pifithrin-α, p-Nitro, Cyclic (PFN-α),是细胞通透性的 p53 抑制剂。Pifithrin-α, p-Nitro, Cyclic 对暴露于 Etoposide 的皮层神经元的保护作用比 Pifithrin-α 强一个数量级 (ED50=30 nM).货号: HY-123076 ,CAS:60477-38-5
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Rocha S, Campbell KJ, Roche KC, et al. The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro. BMC Mol Biol. 2003 Sep 11;4:9. PMID: 12967348. Kanno S, Kurachi K, Tomizawa A, et al. Pifithrin-alpha has a p53-independent cytoprotective effect on doc...
Pifithrin-β(Synonyms: PFT β; Cyclic Pifithrin-α) Pifithrin-β (PFT β) 是有效地p53抑制剂,IC50值为 23 μM。 Pifithrin-βChemical Structure CAS No. :60477-34-1 *Please selectQuantitybefore adding items. Pifithrin-β 的其他形式现货产品: Pifithrin-β hydrobromide 所有产品仅用作科学研究或药证...
A convenient one-pot synthesis of thiazol-2-imines: application in the construction of pifithrin analogues For the first time a reaction intermediate has been isolated giving further insight into the mechanism of thiazol-2-imine formation. The first step of the ... S Murru,CB Singh,V Kavala,...