Myoband Carbs is a relatively straightforward, time-released blend of the common carbohydrate sources, pure cyclic dextrin, fructose, and maltodextrin, combining to provide 48.4g of carbs with 11.8g of that sugar in a 50g serving. Once again, it is a very simple product, and that simplicity ...
Dry powder inhalersSpray-dryingSugarsThis work aims to identify a suitable formulation for the pulmonary delivery of combinations of inhalational drugs using highly branched cyclic dextrin (HBCD) macromolecules. We compared the effectiveness between powders prepared from HBCD with those prepared from five...
The powder was resuspended in buffer B (0.6 M sorbitol, 0.1 M KCl, 1.0 mM EDTA, 2.0 mM DTT, 1.0 mM PMSF, 50 mM Tris-HCl, pH 7.5) and lysed using an ultrasonic cell disruptor (0 °C for 30 min). The suspension was centrifuged at 8000g and 4 °C for 10 min and the ...
1. White amorphous powder 2. Solubility in methanol 3. Molecular weight of 807, as determined by FAB mass spectroscopy which is consistent with the assigned structure in FIG. 1. It is to be noted that in the aforementioned fermentation reactions and the post-treatment of the fermentation ...
such as starch or dextrins, disaccharides, such as maltose or cane sugar, monosaccharides such as glucose or xylose, sugar alcohols such as mannitol or glycerol and naturally occurring mixtures such as malt extract, molasses or whey powder. Suitable nitrogen sources are all customary organic and ...
dextrin, glycerol, vegetable oil, or the like may be used as the carbon source. As the nitrogen source, meat extract, peptone, gluten meal, cottonseed meal, soybean powder, peanut powder, fish meal, corn steep liquor, dry yeast, yeast extract, ammonium chloride, ammonium sulfate, ammonium ni...
Dry powder inhalersHighly branched cyclic dextrinSpray dryingThis study aimed to investigate the feasibility of using highly branched cyclic dextrin (HBCD) as an additive agent for dry powder inhalers (DPIs) because the currently approved excipients for pulmonary administration are limited in number. ...
Fukami, T., Furuishi, T., Suzuki, T., Hidaka, S., Ueda, H., Tomono, K.: Improvement in solubility of poorly water soluble drug by cogrinding with highly branched cyclic dextrin. J. Incl. Phenom. Macrocycl. Chem. 56 , 61–64 (2006)...
The supplementary material may include hydroxypropyl methyl cellulose-400, hydroxypropyl methyl cellulose-4000, lactose, microcrystalline cellulose, compressible starch, fine silica gel powder and magnesium stearate. The preparation process of the cyclodextrin inclusion compound of prazosin hydrochloride includes ...
Highly branched cyclic dextrinSpray dryingHBCD is a promising excipient for dry powder inhalers.HBCD forms aggregation structures in aqueous solution that are 20–30nm in size.The aggregation mechanism differed between hydrophilic and hydrophobic drugs.The particle formation with HBCD differed between ...