a父亲又是一个伟大的不能再伟大的人,他用辛勤的汗水换来了一家人的幸福安康 正在翻译,请等待...[translate] a我需要暂停一个月 I need to suspend for a month[translate] acyclic AMP response element binding protein 循环安培反应元素约束蛋白质[translate]...
Scott Bitner R (2012) Cyclic AMP response element-binding protein (CREB) phosphorylation: a mechanistic marker in the development of memory enhancing Alzheimer’s disease therapeutics. Biochem Pharmacol 83(6):705–714. : 10.1016/j.bcp.2011.11.009...
Cyclic AMP response element binding protein (CREB) is a member of a family of transcription factors that is activated by neuronal activity. The C-terminal end contains a basic domain that binds to the pallindromic cAMP response element (CRE) composed of TGACGTCA while oth...
1) cyclic AMP response element-binding protein 环磷酸腺苷反应单元结合蛋白1. The contents of acetylcholine(Ach)、cholinesterase(ChE) activity、cyclic AMP response element-binding protein(CREB) and. 方法:采用右侧海马注射β淀粉样肽(β-amyloid peptide,Aβ)25-35制作AD大鼠模型,用穿梭箱检测其行为学;...
c-AMP反应元件结合蛋白 1. Objective To explore the effect of status epilepticus(SE) on learning and memory and expression of phosphorylatedc-AMP response element binding protein(pCREB) in hippocampus in developmental rats. 目的探讨癫癎持续状态(SE)对发育期大鼠学习记忆功能及海马磷酸化的c-AMP反应元件...
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Specifically, the cAMP response element-binding protein (CREB) interacts with the cAMP response element (CRE) DNA site with high affinity, while it binds the CAAT/enhancer-binding protein (CEBP) DNA site with low affinity. Despite the selectivity of CREB for the CRE site, CREB-dependent ...
We hypothesized that activation of the protein kinase A signaling pathway may inhibit NF-kappaB-mediated transcription by phosphorylating proteins, such as cAMP response element-binding protein (CREB), which compete for limiting amounts of the coactivator CBP. Here, we show that the amino-terminal ...
The phosphorylation of cyclic AMP response element binding protein (CREB) was immunohistochemically examined in the rat brain at 3.5 h, 12 h, 24 h, 48 h, 7 days and 14 days of recirculation after focal ischemia, which was induced by occlusion of the middle cerebral artery for 1.5 h. Brai...
Previous experiments showed that the expression and phosphorylation levels of cyclic AMP-response element binding protein (CREB) are important factors that regulate oligodendrocyte differentiation. The present study was designed to determine whether CREB phosphorylation advances oligodendrocyte differentiation or ...