Further experimental work confirmed this and indicated that cyclic AMP has an even broader role in the regulation of smooth muscle function (2): compounds inhibiting cyclic AMP phosphodiesterase and thereby increasing intracellular cyclic AMP, consequently relax the smooth muscle (3); they also ...
The meaning of CYCLIC FUNCTION is a mathematical function that changes in value by an additive constant whenever its variable arguments pass continuously through a cycle of values.
same cell of multipleenzymeswhich essentially perform the same reaction of hydrolyzingcyclic nucleotides, does not merely serve a survival or protective function, but rather allows cells to use distinct subsets of differentially regulated and localized PDEs to specifically and selectively regulate and ...
We predict that a 25% loss of heteromeric KCNQ2/KCNQ3-channel function is sufficient to cause the electrical hyperexcitability in BFNC. Drugs raising intracellular cAMP may prove beneficial in this form of epilepsy. 展开 关键词: Cyclic AMP Epilepsy Potassium Channels DNA Complementary KCNQ2-...
3.3Cyclic AMP response element binding protein (CREB) The cyclic AMP response element binding protein (CREB) is a transcription factor of theleucinzipper family and is typically activated by phosphorylation atproline133 viaprotein kinase A(PKA) or calmodulin kinase (Mayr and Montminy, 2001).CREB...
In addition to research on the substrates of cAMP-dependent protein kinase, this chapter describes current research on the regulation, physiology and possible differential function of the two major isozymes of this enzyme. Numerous studies have shown that protein kinase is compartmentalized within the ...
It is at this step that it says "Expression.Error: A cyclic reference was encountered during evaluation.". But this is exactly what I need. I want those processed this month to be excluded from processing next month. Any ideas how to accomplish this?
adenosine monophosphate, adenylic acid, AMP - a nucleotide found in muscle cells and important in metabolism; reversibly convertible to ADP and ATP adenosine diphosphate, ADP - an ester of adenosine that is converted to ATP for energy storage adenosine triphosphate, ATP - a nucleotide derived from...
We have designed a function-integrated alicyclic polymer, poly[carboxy-tetracyclo(4.4.0.1.1)dodecyl methacrylate] [poly(CTCDDMA)], which has both a dry- etching resistant unit (the tetracyclododecyl group) and a carboxyl substituent, inducing alkaline-solubility. This polymer exhibits good dry-...
function in a mammal, wherein said medicament is released from a surface of an implantable medical device. For example, provided is a vascular stent provided with a 4,7 cyclic Ang(1-7) analog having the amino acid sequence Asp-Arg-Val-Abu-Ile-His-Ala, Asp-Arg-Val-Ala-Ile-His-Abu or...