Cyanidin-3-O-glucoside (C3G) is a kind of anthocyanin which shows strong anti-inflammation, anti-tumor and anti-oxidant properties. This paper was designed to explore the potential effects of C3G on diabetic retinopathy (DR). C57BL/6 mice were administrated with streptozotocin (STZ) or ...
摘要: C3G suppressed hepatic oxidative stress and reduced hepatic lipid accumulation and inflammation.C3G enhanced Parkin-mediated mitophagy.C3G enhanced mitophagy by activating the AMPK pathway.关键词: Cyanidin-3-O-glucoside Alcoholic liver disease mitophagy AMPK pathway ...
C3G and peptides decreased AGTR-1 mRNA in myotubes from obese T2DM individuals. Abstract Incidence of type II diabetes mellitus (T2DM) is rapidly increasing worldwide. This study aimed to investigate whether cyanidin-3-O-β-glucoside (C3G), or peptides with angiotensin converting enzyme (ACE...
Cyanidin-3-O-尾-glucoside (C3G), an anthocyanin in blueberry, and peptides with angiotensin converting enzyme (ACE) inhibitory activity derived from yoghurt are potentially beneficial for numerous health conditions including improving insulin resistance and glucose intolerance. In this study, the ...
2F3G (2), while the other two peaks were tentatively assigned to be diastereomers at the 2-position of 5,7,3ʹ,4ʹ-tetrahydroxyflav-3-en-3-ol 3-O-glucoside (Fig.3b,c)33,34. Following evaporation and preparative HPLC purification of the resulting residue, pure 2F3G (2) was ...
(C3G), a type of anthocyanin, possesses powerful anti-inflammatory activities. In this study, the anti-inflammatory effects of C3G were investigated in LPS-stimulated BV2 microglia. The results indicate that pretreatment with C3G significantly suppresses microglial activation and the production of ...
Cyanidin-3-O-glucoside (C3G), a member of blueberry ACN family, can inhibit the tumor necrosis factor-α (TNF-α)-induced proliferation of vascular smooth muscle cells (VSMCs). However, the effects of C3G on VSMC apoptosis and migration remain unclear. This study was thus conducted to...
We speculate that the function of black rice may be related to its main substance, C3G. Therefore, the aim of this study was to investigate the effect of C3G on alcoholic liver injury in mice and to explore its possible mechanism through gut microbiota. 2. Materials and Methods 2.1. ...
However, a simple substitution at R3 [–H (Pg3G) by –OH (Cy3G)] modifies Cy3G bioaccessibility, absorptivity, and metabolism within enterocytes [34]. Lastly, rare anthocyanidins such as 3-deoxy-anthocyanidins, hydroxylated at the 6th position, 5, 7, 3 , 5 -O-glycosilated, C-...
The overexpression of miR4 impaired the protective effects of C3G on the injured HUVECs by increasing cell apoptosis and inflammation. The findings outlined in the current study confirmed the protective effects of C3G on EC function, which was associated with the down‐regulation of miR4 and ...