The data represent means plus or minus SEM (n = 2). We thus evaluated the effect of βarr2 expression on migration of CXCR4wt- or CXCR41013-expressing HEK cells toward CXCL12. Cells were transfected with βarr2-GFP or the pN1-eGFP vector, and CXCL12-induced migration of cells with ...
Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 2006;25:977–988. 46. Askmyr M, Sims NA, Martin TJ, et al. What is the true nature of the osteoblastic hematopoietic stem cell niche? Trends Endocrinol Metab ...