但是ASC如何在营养过剩期间减少细胞衰老的机制还不清楚。这篇文章就提出了自己的猜想,他们认为这个过程与巨噬细胞有关。 Adipogenesis and metabolic health. Nat. Rev. Mol. Cell Biol. (2019) https://doi.org/10.1038/s41580-018-0093-z. 他们首先通过流式检测了脂肪组织内巨噬细胞的数量,发现相较于SAT,VAT...
但是ASC如何在营养过剩期间减少细胞衰老的机制还不清楚。这篇文章就提出了自己的猜想,他们认为这个过程与巨噬细胞有关。 Adipogenesis and metabolic health. Nat. Rev. Mol. Cell Biol. (2019) https://doi.org/10.1038/s41580-018-0093-z. 他们首先通过流式检测了脂肪组织内巨噬细胞的数量,发现相较于SAT,VAT...
参考文献: Sirkis, D.W., Warly Solsberg, C., Johnson, T.P. et al. Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy. Genome Med 15, 53 (2023). https://...
另外,2022年6月23日,中国科学院上海药物研究所赵强,吴蓓丽,王明伟及杨德华共同通讯在Cell Research在线发表题为“Structural insights into ligand recognition and selectivity of somatostatin receptors”的研究论文,该研究报告了不同状态...
(Nishiyori et al., 1998). CX3CL1 can either be membrane-bound or released from the cell surface after constitutive or inducible cleavage byproteasesof theADisintegrinAndMetalloprotease (ADAM) family (Garton et al., 2001; Hundhausen et al., 2003). CX3CL1 is one of the ‘find me’ ...
CX<sub>3<sub>CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance, ArtículoDendritic cells (DCs) and macrophages are critical to innate and adaptive immunity to the intestinal bacterial microbiota. Here, we identify a myeloid-derived mu...
graded CX3CR1 expression provides a strategy to translate the behavior of distinct T cell differentiation states across species. DOI: 10.1016/j.immuni.2023.06.025 Source:https://www.cell.com/immunity/fulltext/S1074-7613(23)00282-0
期刊名称:Cell Host and Microbe时间:2018年 影响因子:15.753 一、背景 “生态失调”可能是代谢、神经和炎症疾病的后果和原因。研究表明,肠道真菌失调可能调节宿主免疫,进而影响肠道和肺部疾病。真菌失调可在两种主要情况下发生:首先,抗生素治疗消除了在体内平衡过程中促进抵抗真菌定植的细菌。其次,抗真菌药物治疗会促进耐...
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance Science, 307 (2005), pp. 254-258 10.1126/science.1102901 1:CAS:528:DC%2BD2MXisVKltQ%3D%3D, 15653504 CrossrefView in ScopusGoogle Scholar 13 C Manta CX(3)CR1(+) macrophages support IL-22 production by...
and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines...