2009. Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay. PLoS One 4:e4848. doi:10.1371/journal.pone.0004848.Haley NJ, Seelig DM, Zabel MD, Telling GC, Hoover EA (2009) Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay. ...
2). In blood samples from PrP 96GS animals, we observed 57.1% (8/14) detection accuracy in the early pre-symptomatic CWD stage and a similar detection accuracy of 58.3% (7/12) in the late pre-symptomatic stage. For the PrP 96SS group, only 5 samples from animals at the early pre-...
Detection of PrPCWD in Postmortem Rectal Lymphoid Tissues in Rocky Mountain Elk (Cervus Elaphus Nelsoni) Infected with Chronic Wasting Disease D. (2006). Detection of PrPCWD in postmortem rectal lymphoid tissues in Rocky Mountain elk (Cervus elaphus nelsoni) infected with chronic wasting disease.....
Chronic wasting disease (CWD) is a prion disease circulating in wild and farmed cervid populations throughout North America (United States and Canada), Europe (Finland, Norway, Sweden), and South Korea. CWD is a long-term threat to all cervid populations and to cervid hunting heritage, with ...
In the present study, we optimized the detection of CWD-prions in fecal samples from naturally infected, pre-clinical white-tailed deer by comparing protocols aiming to concentrate CWD-prions with direct spiking of the sample into the PMCA reactions. Results of this screening were compared with ...
IHC and PMCA CWD detection in offspring born to mock and CWD-infected muntjac.Amy V. NallsErin McNultyJenny PowersDavis M. SeeligClare HooverNicholas J. HaleyJeanette HayesKlugKelly AndersonPaula StewartWilfred Goldmann
Here, we describe the detection of CWD prions in naturally-infected, farmed white-tailed deer (WTD) fetal tissues using the Protein Misfolding Cyclic Amplification (PMCA) technique. Prion seeding activity was identified in a variety of gestational and fetal tissues. Future studies should demonstrate...
Detection of CWD prions in naturally infected white-tailed deer fetuses and gestational tissues by PMCAdoi:10.1038/S41598-021-97737-YFrancisca Bravo RisiPaulina SotoThomas EcklandRodrigo MoralesNature Publishing Group
Rapid detection of CWD PrP: comparison of tests designed for the detection of BSE or scrapie. Transbound. Emerg. Dis. 59 (5), 405-415.Blasche T, Schenck EV, Balachandran A, Miller MW, Langenberg J, Frolich K, et al. Rapid Detection of CWD PrP: Comparison of Tests Designed for the...
Highly sensitive tests for the detection of prion proteins are an important tool both for the design of effective disease surveillance and control strategies and the safety of the food chain. Thus, this study contributes to the emergency preparedness against CWD.Blasche, T.Schenck, E. V....