13 Recent updates to the United States Pharmacopeia (USP) Chapter General <800> will require implementation of additional safety standards for hazardous drug handling. These updates aim to improve safety for all health care workers.13 However, safety practice gaps are problematic. A recent onlin...
Also, the United States Pharmacopeia (USP) has adopted a new Chapter on Pyrrolizidine Alkaloids <1567> Pyrrolizidine Alkaloids as Contaminants in USP-NF 2023 Issue 3 [76]. All the regulators indicate that the presence of PAs in food products can be minimized or prevented by the application of...
United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA). Nutrients 2021, 13, 2742. [Google Scholar] [CrossRef] [PubMed] Hou, D.; Tang, J.; Feng, Q.; Niu, Z.; Shen, Q.; Wang, L.; Zhou, S. Gamma-aminobutyric acid (GABA): A comprehensive review of ...
Together, new insights, increasing knowledge, and rapid technical development have led regulatory authorities to adjust pharmaceutical approval and quality regulations regarding particulates, e.g., United States Pharmacopeia (USP) <787> or <788> for parenteral formulations [25,26]. Both USPs set limit...
One important factor in analyzing a final drug product is to ensure that the composite sample of the final drug products is within specification guidelines. The guidelines are determined within the scope of the United States Pharmacopeia (USP) requirements [139]. The challenge with tablet scoring ...
The quality of this extract is defined in the United States Pharmacopeia (USP 28). Between 65% and 75% of Pycnogenol are procyanidins comprising catechin and epicatechin subunits with varying chain lengths. Other constituents include polyphenolic monomers, phenolic or cinnamic acids and their ...
LC Technique High-performance liquid chromatography (HPLC) with a FLD detector is perhaps the most commonly and widely used approach for AF determination in herbal medicine matrices, and has been recommended in pharmacopeia in numerous countries and regions [44,47,50–52]. AFB1 and AFG1 ...