Treatment of pediatric type 2 diabetes (T2D) is extremely challenging for many reasons. Chief among these are the fact that metformin had been the only drug approved for use in adolescents with T2D for more than 20 years based on the results of a randomized clinical trial. Insulin was ...
The escalating global epidemic of type 2 diabetes mellitus has focused attention on the devastating consequences of protracted hyperglycemia. Early and effective intervention to control blood glucose is a fundamental principle of treatment guidelines, requiring assiduous use of current therapies. However, ma...
Objective: The major drawback of current treatment of diabetes is challenging due to resistance to antidiabetic agents their side effects. Chromenes occurs naturally in plants and plays role of anticoagulant activity. Guanidine plays role of antidiabetic activit...
Current state of treatment of diabetes mellitusJanzen, Sandra
• Since every diabetes treatment has beneficial and adverse effects, there is no general therapy for all patients. • Bone weakening is now recognized as a complication of diabetes that also requires attention for treatment. •DM treatments are based on decrease of oxidative stress, inflammatio...
international experts on the most significant developments in the field. By presenting clear, insightful, balanced reviews that emphasize recently published papers of major importance, the journal elucidates current and emerging approaches to the diagnosis, treatment, management, and prevention of diabetes....
Comparison of bone marrow mesenchymal stem cells with bone marrow-derived mononuclear cells for treatment of diabetic critical limb ischemia and foot ulcer: a double-blind, randomized, controlled trial. Diabetes Res Clin Pract 2011; 92: 26–36. PubMed Google Scholar Yurugi-Kobayashi T, Itoh H...
Many of the preclinical strategies being explored for the treatment of one form of Batten disease could have applications across multiple subtypes of Batten disease and even other lysosomal storage disorders. Investigators now recognize that a single treatment might not be sufficient to halt disease pro...
The EPHESUS (Eplerenone Post-Acute Hospitalization and Survival Study in Heart Failure) trial enrolled patients with a reduced ejection fraction and evidence of HF (or diabetes mellitus) after recent MI (33). There was an interaction between baseline sCr and the effect of treatment on all-cause ...
Conclusion: To further improve the diabetes management in Germany a more effective control of blood glucose, blood lipids and blood pressure should be performed. An overall optimisation in the current treatment of diabetes might improve quality of life, and decrease costs for treatment of diabetes ...