- 《International Journal of Health Sciences & Research》 被引量: 1发表: 2014年 Evaluation of red cell indices and manual reticulocyte parameters in iron deficiency, vitamin B12 deficiency and beta thalassemia minor patients in a terti... Shabeera ShamsuddinK. UpadhyayaS. SudhakarAejaz Ahamed Z....
Current perspectives of fertility and pregnancy in thalassemia. Expectation to have a family is an important aspiration for a better quality of life for the adults with thalassaemia syndrome. Spontaneous fertility can o... R Bajoria,R Chatterjee - 《Hemoglobin》 被引量: 35发表: 2009年 加载更多来...
These severe adverse events represented a turning point toward the development of alternatives to viral vectors. However, over the years, research on viral vectors also led to significant improvements in their safety. More recently, CAR-T and gene therapy treatments based on viral vectors have been...
In 2007, the Children’s Interstitial Lung Disease Research Cooperative of North America proposed a new classification of chILDs for affected children under 2 years of age based on a retrospective review of 186 lung biopsies [4]. The classification was widely accepted and included in the 2013 ...
the clinical applications for intima-media thickness measurement in children with known risk factors such as obesity, liver steatosis, hypercholesterolemia, diabetes, hypertension, systemic inflammatory diseases, cancer survival, kidney and liver transplant, and sickle cell disease or beta thalassemia major....
and techniques that have been used in OA research in recent years. First, we focused on the epigenetic regulation of OA, with a particular focus on DNA methylation, histone modification, and microRNA regulation, which have been implicated in OA, and potential epigenome-based therapeutics for OA...
On the horizon: targeting “next-generation” checkpoints Although CTLA-4 and PD-1 blockade are the focus of the basic research and clinical attention, continued exploration of additional checkpoints may lead to development of combination treatment strategies that can improve responses and expand immun...
Third, T2* sensitivity to iron at 3.0T may be exploited to better delineate individuals with iron-overload as seen in patients with Thalassemia [36, 37]. However, the quantification of actual T2* values in areas of very high iron concentration may be more difficult at 3.0T due to the ...
(1994). Nonsense codon mutations in the terminal exon of the beta-globin gene are not associated with a reduction in beta-mRNA accumulation: A mechanism for the phenotype of dominant beta-thalassemia. Blood. https://doi.org/10.1182/blood.V83.8.2031.bloodjournal8382031 Article PubMed Google ...
(pNETs) than chromosomal gain. Somatic mutations in multiple endocrine neoplasia type 1 and death domain associated protein/α-thalassemia, mental retardation, X-linked have been identified in 44% and 43% of pNETs, respectively, while 14% of tumor samples exhibited mutations in mTOR and ...