First published July 11, 2012; doi: 10.1152/ajprenal.00547.2011.-Chloroquine, a widely used anti-malaria drug, has gained popularity for the treatment of rheumatoid arthritis, systemic lupus erythematosus (SLE), and human immunodeficiency virus (HIV). Unfortunately, chloroquine may also negatively ...
No other chronic inflammatory disease is currently receiving more attention from basic scientists than rheumatoid arthritis (RA). Topics of intense research are HLA disease association, peculiarities of the synovial T- and B-cell repertoire, changes of synoviocytes and cytokine profiles as well as anim...
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease of unknown aetiology, leading to progressive damage of bone and cartilage with functional impairment and disability. Whilst the ...
Rheumatoid arthritis (RA) is a complex autoimmune disease characterized by chronic inflammation of the synovial tissue, where T cells play a central role in pathogenesis. Recent research has identified T peripheral helper (Tph) cells as critical mediators of local B cell activation in inflamed tissue...
One promising area of research involves the use of GPS technology and other environmental sensors to collect real-time data on an individual’s exposure to air pollution, water quality, and other environmental factors that may increase their risk of CAD [178]. This can be valuable in developing...
ORIGINAL RESEARCH Article Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation Qiu Dong, Jiayang Wu, Huaguo Zhang, Xinhui Chen, Xi Xu, Jifeng Chen, Changzheng Shi, Liangping Luo & Dong Zhang Pages: 637-652 Publish...
Current concepts in the pathogenesis of early rheumatoid arthritis. Current concepts in the pathogenesis of early rheumatoid arthritis. Best Pract Res Clin Rheumatol 2009;23:3748.Pratt AG, Isaacs JD, Mattey DL (2009... AG Pratt,JD Isaacs,DL Mattey - 《Best Practice & Research Clinical Rheu...
This review mainly focuses on the current pharmacologic and regenerative therapeutic approaches for OA treatment. It includes therapy that has been confirmed clinically effective and used for decades, as well as therapy that shows promise in preclinical research and can potentially be translated for futu...
Comprehensive overview of microRNA function in rheumatoid arthritis ArticleOpen access24 January 2023 Single-cell RNA sequencing in orthopedic research 24 February 2023 Introduction Osteoarthritis (OA) is the most common debilitating disease, a leading cause of disability, and is characterized by chronic ...
Development of type 1 diabetes in a patient treated with anti-TNF-alpha therapy for active rheumatoid arthritis. Diabetologia. 2009;52(7):1442–4. https://doi.org/10.1007/s00125-009-1381-0. Article CAS PubMed Central PubMed Google Scholar Mastrandrea L, Yu J, Behrens T, Buchlis J, ...