Some issues remain at the forefront of the controversy involving stem cell research - legislation, ethics and public opinion, cost and concentration methods. As is true with any new technology, the enthusiasm for this technology that has potential to influence virtually every orthopedic case ...
Research involving the use of BC and CNCs for tissue engineering applications was reviewed by Dugan et al.in 2013 [34]. The surface modification of BC with bioactive peptide sequences using cellulose-binding domains was discussed as a strategy to enhance its bioactivity. The surface charge of CN...
Research in human embryonic stem cells (hESCs) is a rapidly developing scientific field. In this study we collect and evaluate a thorough body of data on the current number of publicly disclosed hESC lines and the extent and impact of scientific work involving the use of these cells. These ...
Table 1. Selected Stem Cell Trials Involving Neural Stem Cells in Glioblastoma. NCT identifier (ClinicalTrials.gov)Type of trialPurposeInterventionPrimary outcome measureTrial statusSponsor and collaborators NCT03072134 Phase I NSC-based virotherapy in combination with standard radiation and chemotherapy for...
cells (nucleoplasmic localization), deregulated genes are linked to viral carcinogenesis, stem cell pluripotency, B cell receptor signaling and cancers. Alternatively, nucleolar Tat in HIV-infected T cells, deregulate genes involved mainly with ribosomal biogenesis [72]. This is the case forDrosophila...
Research involving human embryos, gametes, and stem cells Manuscripts that report experiments involving the use of human embryos and gametes, human embryonic stem cells and related materials, and clinical applications of stem cells must include confirmation that all experiments were performed in accordance...
Pluripotent stem cells (PSCs) hold great promise for drug discovery and regenerative medicine owing to their ability to differentiate into any cell type in the body. After more than three decades of research, including delays due to the potential tumorigenicity of PSCs and inefficiencies in differe...
involving multiple neurotransmitter systems, protein aggregation, neuroinflammation, and dysfunction of various neural circuits. For stem cell therapies to be truly disease-modifying or curative, they would need to address these multiple aspects of PD pathology. Recent research has highlighted additional cha...
Kollmann, for instance, stimulated organoids and Caco-2 cells with a mixture of TNFα, IFN-γ, and IL-1ß [46]. The findings indicated that organoids outperformed the Caco-2 cell line, displaying a heightened sensitivity to inflammatory stimuli. They exhibited responses involving loss of ...
Stem cell-based therapies have emerged as a promising approach for treating various neurological disorders by harnessing the regenerative potential of stem cells to restore damaged neural tissue and circuitry. This comprehensive review provides an in-dep