TAMs, as one of the major tumor-infiltrating immune cell types, can be classified into two distinct subtypes: classically activated M1 macrophages and alternatively activated M2 macrophages. These two functionally different types can interconvert when TME is altered. M1 macrophages are generally regarded...
IJCRR is one of the popular published Healthcare ( physiotherapy journals,Journal of Physiotherapy,Nutrition, Pharmacy, Psychology, Immunology, Anatomy) and Life Sciences journals(Botany, Zoology).
Neonatal Mortality and Prevalence of Practices for Newborn Care in a Squatter Settlement of Karachi, Pakistan: A Cross-Sectional Study During the past two decades there has been a sustained decline in child and infant mortality, however neonatal mortality has remained relatively unchanged... A Afsh...
Viral hepatitis is considered as a significant factor contributing to high morbidity and mortality rates within the global population, thereby affecting the health of millions of individuals [1]. The prevalence of viral hepatitis is primarily linked to five hepatotropic viruses: hepatitis A virus, hep...
Over half the population of England’s prisons in the 18th century were in jail because of debt. Run privately for profit, as were all English prisons until the 19th century, the Marshalsea looked like an Oxbridge college and functioned as an extortion racket. Not a fun place to reside: ...
According to the farmers, a Swedish wolf population of up to 460 slaughtered over 340 sheep in 2021. "The culling is very vital to curb the spread of the wolves," said Gunnar Gloersen, Predator manager at the Swedish Hunters' Association.[4] Bus Crash Leaves 2 Kids Dead: On Wednesday,...
No child in the study population had received the varicella vaccine. This reflects low vaccination coverage in the region from which the patients included in the study came from. These data concur to demonstrate that universal varicella vaccination of children is beneficial not only in the ...
a result, these Tregs express immune checkpoint molecules (e.g., PD-1 and CTLA-4) to suppress the effector functions of T cells [184]. MDSCs are a highly heterogeneous population of myeloid cells that contribute to tumor immunosuppression [187]. GBM cell-derived macrophage migration inhibitory...
Studies on the impact of sleep duration and TNF-α have shown that sleep restriction generally increases TNF-α levels [29,30,31]. The Cleveland Family Study, a population level evaluation, showed that each hour less of sleep on polysomnography was associated with an 8% increase in TNF-α....
By comparison, in one general surgical unit of a government hospital, the Civil Hospital, Karachi, which caters for an indigent population, the frequency of cholecystectomies was 9% (67/753) during that year [1]. It appears that gallstone disease is common to all socioeconomic groups in ...