Even without the presence of glutamate, vitamin C alone induces lipid peroxidation in a dose-dependent manner. Statistically significant oxidant effects were shown at all doses tested (from 25 to 200 μM) and when added together with glutamate, produced an additive amount of ROS damage [47]. ...
A recent study has illustrated an increased efficacy of Aminexil, a keratin fibers stimulator and hair growth promoter, loaded in a nanostructured lipid carrier (NLC) in chemotherapy-induced alopecia rats showing an increase in hair growth promotion compared to the use of the commercial product alon...
The Role of Nutraceuticals in the Optimization of Lipid-Lowering Therapy in High-Risk Patients with Dyslipidaemia Purpose of Review: We aimed to summarize recent guidelines, position papers, and high-quality clinical research relating the use of nutraceuticals in the m... PE Penson,M Banach - 《...
Lipid abnormalities include increased serum triglycerides, very low-density lipoprotein, and intermediate-density lipoprotein and decreased high-density lipoprotein. Elevated total cholesterol is found in 30% of CKD patients without nephrotic syndrome and in 90% with nephrotic syndrome compared with 20% ...
Diabetic retinopathy (DR), a well-known microvascular complication of diabetes mellitus, remains the main cause of vision loss in working-age adults worldwide. Up to now, there is a shortage of information in the study regarding the contributing factors
The effect of 2.45 GHz radiation on histology and the level of lipid peroxide in rats was demonstrated (2 h a day for 35 days with PD of 0.2 mW/cm2 and estimated SAR of 0.14 W/kg) [41]. Oxidative brain and liver damage and disturbed development of newborn rats were reported as a ...
and had higher pulmonary vascular resistance than those with 0–2 births [93]. The authors hypothesized that pregnancies contribute to systemic inflammation, with possible mechanisms including adverse lipid profiles, upregulation of the renin–angiotensin–aldosterone system, and increased insulin resistance...
showed good regression performance for the prediction of response to multiple antipsychotic drugs (ROC = 0.87 [95% CI: 0.87–0.88]) [35]. In patients with type 2 diabetes, combining PGS with clinical data such as smoking status, BMI, blood lipid levels, blood pressure, and the use of...
Although no specific studies have been yet performed on ocular diseases, it is worth to mention ALN-VSP02 (Alnylam Pharmaceuticals) since it is a lipid nanoparticle-formulated dual-targets drug candidate. It contains two different siRNAs, chemically modified (with 2′-O-methyl groups to minimize ...
they are enriched in body fluids and easily accessible. Second, due to their lipid bilayer structure, exosomes are stable, which allows them to maintain stability during circulation in the body, sample transportation, and storage, making them crucial for the development of biomarkers using retrospecti...