期刊名称:《Current drug targets-The International journal for timely in-depth reviews on drug targets》 | 2005年第6期 关键词: DNA; Catalytic; RNA; Catalytic; The science and art of healing; Gene Expression; RNA; 催化; 基因表达; 29.NAD(P)H oxidase activation: a potential target mechanism...
Cardiovascular diseases are the leading cause of death, and dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease. During the last several decades, development of drugs that reduce low density lipoprotein-cholesterol has been the focus in the treatment and prevention of dysl...
This journal presents incisive reviews by international experts, on all aspects of pharmacology, including drug discovery and development. Coverage spans such key subjects as epigenetics and epigenomics, chemoinformatics, rational drug design and target discovery, drug delivery and biomaterial, pharmacogenomics...
drug-drug interactions and enzyme kinetics; species scaling and extrapolations; drug transporters; target organ toxicity and inter-individual variability in drug exposure-response; extrahepatic metabolism; bio-activation, reactive metabolites, high-throughput screening, drug targets and structure-activity relat...
Current Cancer Drug TargetsCAPubMedAJSCIEJCR:Q3中科院4区 发文量1,777 被引量51,255 影响因子(2023)2.664 Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular ...
In this review, discussion of the effects of different drug target sites on the disease modification will be compiled. Methods: It is a review to discuss in detail the efficacy of different drugs for the disease modifying effect of their respective target site. Results: Alzheimer's disease have...
After initial strategies targeting inotropism and congestion, the neurohormonal interpretative model of heart failure (HF) pathophysiology has set the basis for current pharmacological management of HF, as most of guideline recommended drug classes, including beta-blockers, angiotensin-converting enzyme in...
Journal Title:Current Drug Metabolism Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism, pharmacokinetics, and drug disposition. The journal serves as an international forum for the publication of full-length/mini review, research articles and guest edit...
The journal covers the following areas: In vitro systems including CYP-450, enzyme induction and inhibition; Drug-drug interactions and enzyme kinetics; Pharmacokinetics /toxicokinetics / species scaling and extrapolations; P-glycoprotein and transport carriers; Target organ toxicity and inter individual ...
is critically depending on the signaling of androgen receptor (AR). Current major drug target for...