They then employed the HSFCM for the single EV detection that can detect EVs between Biosensors 2023, 13, x FOR PEER REVIE4W0 nm and 200 nm in diameter with an analysis rate of 10,000 particles/min (Figure 3B,C). HSFCM offers a sensitive way to measure the size of single EVs and ...
However, since the response rate to these inhibitors is low, exploration of efficacy-predictive biomarkers identifying patients expected to respond to these inhibitors has been conducted worldwide, and close attention has been paid to the tumor mutational burden as one possible predictor [79,80]. ...
The biosensor principle was based on the measurement of the inhibition rate of the analyte in the presence of fixed amounts of acetylthiocholine chloride. DRs were 10−12–10−8 g/mL, 5 × 10−13–5 × 10−9 g/mL, and 10−13–5 × 10−9 g/mL, with LODs of 3.2 × ...