pulse width does not significantly change clinical efficacy, but will increase current consumption and may lower the threshold for side-effects, consequently narrowing the therapeutic window, and thus reducing the possibility of “titrating” amplitude in order to achieve the highest possible benefit. ...
derived neurotrophic factor (BDNF) performs a regulatory function in synaptic plasticity, neural differentiation, and cell death procedures. Multiple regions of the brain, especially the hippocampus, have been found to contain BDNF [117], and there is a correlation between low BDNF levels and AD [...
In contrast, the jumping tasks did not benefit from this stimulation, probably because the particular experience of the participants did not leave any room for a potential optimization in motor planning of such a usual task. This study has some limitations. First, the lack of retribution/...
A clear benefit of the study is the access to controlled and monitored tDCS treatment, which is not available as a standard treatment for ASD. Potential benefits for participants receiving real tDCS stimulation are improved social communication symptoms in ASD. The present study investigates tDCS as...
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing cells as in cytotoxic chemotherapy. The Response Evaluation Criteria in Solid Tumor (RECIST) system has been used to assess...
To test the robustness of the viral clearance process, it should be practiced with both new and aged chromatography media. This is important in order to establish the maximum number of cycles that can be run. Virus filtration With virus filtration progress has been made with fi...
Cryoprecipitate (1 unit each 10 kg of body weight) is used, when maximum amplitude (MA) of TEG is less than 50 mm or plasma fibrinogen level <100 mg/dL [53]. Platelet count below 50,000/mm3 is another cause of MA <50 mm and should be corrected [53]. 8. Intracranial hypertension...
[74]. GA at the doses of 50 and 100 mg/kg in rats increased the hippocampal level of BDNF more than the TMT toxic rats as well as the hippocampal level of TNF-α to benefit AD patients [15]. GA at the dose of 30 mg/kg also increased passive avoidance and memory performance as ...
When CPP-Bevacizumab was applied topically, 0.2% of the initial payload was detected in tissue homogenates through ELISA just after 30 min that was significantly higher than the individual controls. The maximum retinal concentration was obtained just after 45 min with the traces of the fluorescent ...
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing cells as in cytotoxic chemotherapy. The Response Evaluation Criteria in Solid Tumor (RECIST) system has been used to assess...