Researchers from the Los Alamos National Laboratory in New Mexico and Duke University in North Carolina partnered with the University of Sheffield's COVID-19 Genomics UK research group to analyze genome samples published on GISAID, an international resource for sharing genome sequences....
The initial screening was carried out using spiral gradient endpoint (SGE) analysis, with MTZ alone, and with an American Type Culture Collection control strain plus their own strain with a known reduced susceptibility to MTZ.C difficileMTZ MICs of 6 mg/L or more went forward for further analy...
As the use of this platform has increased with the rollout of the ChAdOx COVID-19 vaccine and potential future use of the vector, particularly for viruses and other pathogens endemic to the same areas i.e. Ebola, LASV and Malaria, vector-specific immunity and its potential role in vaccine...
Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently was declared a pandemic by world health organization (WHO) Due to sudden outbreaks, currently, no completely effective vaccine or drug is clinically approved. Several therapeutic strategies ...
On the other hand, whether the current COVID-19 vaccines could effectively resistthe new strain is still under investigation. However, there is very limited information on the current situation of the Omicron variant, such as genomics, transmissibility, efficacy of vaccines, treatment, and ...
"If you look at the structure ofomicronand compare it to the structure of previous strains, including delta, the site where there is the most change from the original strain is the spike protein," says Dr. Andrew Badley, chair of Mayo Clinic's COVID-19 Task Force. ...
Researchers analyzed a SARS-CoV-2 vulnerability form from specimens of serum from 58 individuals with an existing D614G reference strain (Pseudovirus) infection and 19 persons who had obtained two doses in the preceding 6 weeks of Pfizer/BioNTech mRNA COVID-19 vaccine. Both B117 and D614G ...
In lab experiments using non-human primate cells, Kawaoka's team tested a suite of antibody and antiviral therapies against the original strain of the COVID-19 virus and its prominent variants, including the alpha, delta and omicron strains. ...
During the COVID-19 pandemic, the traditional herbal medicine Artemisia afra Jacq. ex Willd., Asteraceae, was widely used as a remedy, and a true media sto
As such, the S-protein has been similarly recognized as a significant target for COVID-19 vaccines. Notably, other studies have reported that the M-protein is capable of inducing the production of nAbs, and the N-protein contains T-cell epitopes in SARS-CoV; these proteins may also offer ...