Cystinuria is an inherited disorder of the dibasic amino acid transport system in the proximal tubule and the small intestine. Two responsible genes have been identified, the SLC3A1 on chromosome 2 and the SLC7A9 on chromosome 19. The inability of renal tubules to reabsorb cystine and the ...
C Cassinello,E Moreno,A Gozalo,... - 《Dig Dis Sci》 被引量: 221发表: 2003年 Glomerular filtration rate assessment in individuals after orthotopic liver transplantation based on serum cystatin C levels Individuals after orthotopic liver transplantation (OLT) often show renal dysfunction, which may...
Cys31, Cys47, and Cys195 May Not Be Involved with the Disulfide Bond Formation Within the BinA Molecule The disulfide bond is a covalent bond that links 2 cysteine residues [14]. This bond plays an important role for maintaining 3D structure and function of some proteins such as growth horm...
By proteomic analysis, we found a rhodanese-like protein(RhdA) from Acidithiobacillus ferrooxidans ATCC 23270 whose C-terminal contained a cysteine motif (Cys-XX-Trp-XX-Cys), known to bind iron–sulfur clusters. But so far, there were no articles to confirm the existence of iron–sulfur clus...
Here utilizing an eddy-permitting ocean model (NEMO), we find that the complete removal of the New Zealand plateau leads to a smaller fraction of EAC transport heading east and more heading south, with the mean separation latitude shifting >100 km southward. To examine the underlying dynamics,...
Re: Saravakos et al.: Cystinuria: Current Diagnosis and Management (Urology 2013;83:693-699)PizzaR.MarzuilloP.GuarinoS.La MannaA.UROLOGY -NEW JERSEY THEN NEW YORK-
Rare diseases (RD) refer to a collection of approximately 5,000-8,000 individual diseases that have a low prevalence and are often genetic in origin. While RD can manifest throughout life, they frequently affect children and newborns. Common characteristics include being severe, disabling, life-...
This bias is not explained by a linear response to differences in wind stress. The climate change simulations show that regional atmospheric CMIP5 MMM anomalies drive 73% of the projected 12 Sv increase in EAC extension transport whereas the remote ocean boundary conditions and regional radiative ...
Phytochemicals: Current strategy to sensitize cancer cells to cisplatinChao-Yue Sun aQian-Yu Zhang bGuang-Juan Zheng aBing Feng aBiomedicine & Pharmacotherapy
Thus, the European Organisation for Research and Treatment of Cancer (EORTC) Gastrointestinal Tract Cancer Group (GITCG) and the Japan Clinical Oncology Group (JCOG) Stomach Cancer Study Group (SCSG) initiated a collaboration to develop an optimal treatment strategy for LMGC. Before planning a ...