Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes. Current ...
Current Cancer Drug TargetsMitsiades CS, Mitsiades N, Koutsilieris M (2004) The Akt pathway: molecular targets for anti-cancer drug development. Curr ... Constantine S. Mitsiades, Nicholas Mitsiades, Michael Koutsilieris - 《Current Cancer Drug Targets》 被引量: 543发表: 2004年 Wnt / β...
期刊名称:《Current cancer drug targets》 | 2009年第8期 9.Indoleamine 2,3-dioxygenase, an emerging target for anti-cancer therapy. 机译:吲哚胺2,3-二加氧酶,抗癌治疗的新兴目标。 作者:Liu X;Newton RC;Friedman S 期刊名称:《Current cancer drug targets》 | 2009年第8期 10.Breast cancer: ...
Doherty JR, Yang C, Scott KE, Cameron MD, Fallahi M, Li W et al (2014) Blocking lactate export by inhibiting the Myc target MCT1 disables glycolysis and glutathione synthesis. Cancer Res 74(3):908–920 Article CAS PubMed Google Scholar Hong CS, Graham NA, Gu W, Espindola Camacho C...
the signaling of androgen receptor (AR). Current major drug target for advanced prostate cancer is...
enterocytes. It is considered a potential target for weight loss, although concern has been raised because of the theoretical accumulation of fatty acids and monoacylglycerol in enterocytes. Probably due to this, MGAT gets less attention compared to SGAT, and its future as drug target seems ...
Nonetheless, to date, no potential drug candidates have been explored to target CDKN2A/B in cancer treatment. KIT KIT is a type III transmembrane RTK expressed in a variety of human cells.324 The downstream signaling of KIT mainly involves MAPK, PI3K/AKT, and JAK/STAT pathways, thus ...
Mitsiades, Nicholas Mitsiades, Michael Koutsilieris - 《Current Cancer Drug Targets》 被引量: 542发表: 2004年 Targeting AMPK: A new therapeutic opportunity in breast cancer This paper reviews the mammalian Target Of Rapamycin (mTOR) pathway dysregulation in breast cancer, and the current evidence...
期刊名称:《Current drug targets-The International journal for timely in-depth reviews on drug targets》 | 2005年第6期 关键词: DNA; Catalytic; RNA; Catalytic; The science and art of healing; Gene Expression; RNA; 催化; 基因表达; 29.NAD(P)H oxidase activation: a potential target mechanism...
Indole glucosinolate hydrolysis products, such as I3C and DIM, also induce both phase I drug metabolic and phase II/detoxifying enzymes by direct interaction with aryl-hydrocarbon receptor (AhR) or increasing the binding affinity of AhR to xenobiotic response elements (XREs) in target genes [31]...