Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond. Pediatr Diabetes 2008; 9: 4-13.Giannoukakis N,Phillips B,Trucco M.Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond.Pediatric Diabetes. 2008...
Garcia-Loza I, Perna-Barrull D, Aguilera E, et al. Targeting macrophages with phosphatidylserine-rich liposomes as a potential antigen-specific immunotherapy for type 1 diabetes.J Autoimmun [Internet]. 2024;145:103196. (Open in a new window)PubMed(Open in a new window)Web of Science ®(...
Type I diabetes, colloquially referred to as juvenile diabetes, results from an autoimmune destruction of beta cells in the pancreas which normally produce insulin—a hormone which regulates glucose levels in the blood. Doug Melton's revolutionary cells. By Courtesy of Michael S. Segel With limited...
A study has demonstrated that transplanting human embryonic stem cell–derived, insulin-producing cells shielded in capsules made with an optimized biomaterial can achieve long-term cure of diabetes in mice without the need for any immunosuppression. This is a preview of subscription content, log in...
"The ultimate goal of our research is for this knowledge to be translated into being able to manipulatestem cellsto producebeta cellsthat can produce insulin in the laboratory. That could be the key to curing type 1 diabetes. Our finding is a significant step in understanding what makes the ...
In type 1 diabetes we have two problems. There is an absence of insulin-producing beta cells and also an autoimmune attack, which is what killed the cells in the first place. Our lab and others have worked on problem one and I am confident that we are going to get buckets of beta cel...
Type 1 diabetes usually requires life-long treatment with regular insulin injections. DIABECELL is an insulin-producing cell product derived from pigs for the treatment of type 1 diabetes. These islet cells are self-regulating and efficiently secrete insulin in the patient’s body. ...
Type 2 diabetes is caused by a lack of glycogen storage capacity resulting from insulin resistance and excessive glucagon mediated hepatic gluconeogenesis. Diabetes progresses when HbA1c is above 6% and regresses when HbA1c is below 5.5%. Reversal can b
About 15 years ago, I was fortunate enough to be a researcher in a fascinating study among patients who had Type 1 diabetes for an average of 20 years and had no detectable C-peptide in their bloodstream; C-peptide is the marker of internal insulin production. The study gave these patients...
Moringa has been shown to cureboth Type 1 and Type 2 diabetes. Type 1 diabetes is one where the patients suffer from non-production of insulin, which is a hormone that maintains the blood glucose level at the required normal value. Type 2 diabetes is one associated with insulin resistance....