This image, produced by a fluorescence microscope, shows a normal renal proximal tubule, the specific nephron segment in the kidney that is impaired in the rare disease infantile cystinosis. The red, green and yellow regions indicate the presence of different proteins in the tubule and the blue...
Mesenchymal stem cell homing and differentiation Long-term persistence of autologous or allogenic MSCs after a single intravenous infusion has been described in baboons, with levels of tissue engraftment ranging from 0.1 to 2.7% [60]. However, in a chronic kidney disease model, only repeated inject...
And as these children develop, they often require long-term, intensive therapy to prevent further deterioration and loss of kidney function. There is no cure. But there could be. Maybe there should be. In 2002, while working with a collaborator at Harvard University, we injected embryonic ...
Xing X, Zhang C, Shao M et al (2012) Low-dose radiation activates Akt and Nrf2 in the kidney of diabetic mice: a potential mechanism to prevent diabetic nephropathy. Oxid Med Cell Longev. doi:10.1155/2012/291087 PubMedPubMed CentralGoogle Scholar Cheng J, Li F, Cui J et al (2014) O...
In addition, cART does not fully restore health – it increases the risk of non-AIDS disorders such as cardiovascular, kidney, liver and neurological diseases. Moreover, persistent immune dysfunction and inflammation increase the risk of non-AIDS morbidity and mortality (Clifford and Ances, 2013,...
The majority of virally suppressed individuals will experience rapid viral rebound upon antiretroviral therapy (ART) interruption, providing a strong rationale for the development of cure strategies. Moreover, despite ART virological control, HIV infecti
Over years, excess sugar in the bloodstream damages blood vessels and organs. Without effective treatment, diabetics suffer severe complications: blindness, kidney failure, heart disease, amputations, even premature death. On the other hand, too much insulin can cause very low blood sugar, which can...
Maybe you overdid it, because 20K IU daily of D is a lot, like as in likely WAY too much based on anything I’ve ever read on the subject. I’ve read ONLY that 10K IU daily is an absolute upper limit before experiencing some nasty side effects like kidney failure. Otherwise, ...
you trust, understand your disease and advocate for the best treatments for yourself given you’re the one with the most skin in the game. However: So goodbye to allopurinol (kidney protection) and fluconozole (to ward off potential fungal infections which can be a risk after CAR-T) and ...
. In the process, she was administered massive amounts of Heperin to dissolve the clots, which overtaxed her already chemo protocol-compromised kidney function. After eleven days in a local hospital she was transferred to a regional hospital for surgery to amputate her right leg below the knee...