Cuneiform nucleus (CnF)Vasomotor toneRatsNMDAAMPA/Kainite receptorCoCl2The cuneiform nucleus (CnF) is a sympathoexcitatory area involved in the central cardiovascular regulation. Its role in the maintaining vasomotor tone has, however, not yet been clarified. In the present study the effects of ...
CeMe central mesencephalic nucleus CGPn central gray of the rhombencephalon chp chorioid plexus CIC central nucleus of the inferior colliculus CIF compact interfascicular nucleus CLiAz caudal linear nucleus of the raphe, azygoz part CLiZ caudal linear nucleus of the raphe, zygoz part CnF cuneiform...
In order to investigate the role of cuneiformis (CnF) in pain modulation, we evaluated the effect of GABAsubA/sub antagonist (bicuculline) on antinociceptive response of morphine in this nucleus. Eighty five male N-MRI rats, weighing 250-350 g were used, they were maintained on a 12 h ...
Cuneiform nucleus (CnF)Pedunculopontine nucleus (PPN)Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset of Parkinson's disease (PD) patients that is poorly responsive to standard levodopa therapy or deep brain stimulation (DBS) of established PD targets such as ...
Recent research shows greater context dependency in the locomotor functions of this nucleus. Glutamatergic neurons, which contain vesicular glutamate transporter 2 (vGLUT2), regulate context-dependent locomotor speed in the CnF and play a role in defensive behavior. Here, we identify projections from...
Spared descending fibers of the brainstem motor control system can be activated by deep brain stimulation (DBS) of the cuneiform nucleus (CnF), a subnucleus of the mesencephalic locomotor region (MLR). The MLR is an evolutionarily highly conserved structure which initiates and controls locomotion ...
The present study was designed to investigate the nucleus cuneiforms (CnF) neuronal responses during two phases after subcutaneous injection of formalin into the hind paw of rat.Methods: In this study, 76 male NMRI adult rats, weighing 230-320 g were used. Control group (n = 24) was ...
In this study, we achieved the multi-level speed regulation of cyborg rats in the large open field and treadmill by specifically targeting the Cuneiform Nucleus (CnF) of the Mesencephalic Locomotor Region (MLR). Detailed, we measured the influence of each stimulation parameter on the speed ...
Introduction: The underlying mechanism responsible for the cardiovascular response to Hemorrhage (HEM) is still unknown; however, several brain areas, such as the Cuneiform nucleus (CnF) have shown to be involved. In this study, the cardiovascular effect of the CnF during HEM was ...
The presence of opioid receptors in the cuneiform nucleus (CnF), which is a mesencephalic area, and their involvement in the central cardiovascular responses have been shown. Therefore, this study is designed to examine the possible role of mu- () and delta- (δ) opioid receptors in the CnF...