Melatonin and steroid hormones are cytochrome P450 (CYP or P450; EC 1.14.14.1) substrates that have antioxidant properties and mitochondrial protective activities. The mitochondrial intermembrane space (IMS) Cu,Zn-superoxide dismutase (SOD1) is activated after oxidative modification of its critical thiol...
Melatonin and steroid hormones activate Cu,Zn-superoxide dismutase by means of mitochon- drial cytochrome P450. Free Radic. Biol. Med. 50, 1575-1581.Pedro Iñarrea,Alvaro Casanova,Maria Angeles Alava,María Iturralde,Enrique Cadenas.Melatonin and steroid hormones activate intermembrane Cu,Zn-...
目的研究细胞色素P450(cytochrome P450)1B1基因SNP rs1056836在宁夏地区正常汉族人群中的基因型频率、等位基因频率分布特征。方法应用等位基因特异性扩增(AS-PCR)及DNA测序法对410名宁夏汉族正常成人CYP1B1rs1056836C→G位点基因多态性的分布进行测定,并应用χ2检验比较宁夏汉族人群与我国其他地区汉族人群基因频率的分布...
【#孙颖莎谈国球进校园活动感受#】#孙颖莎说很开心看见小朋友热爱体育# 12月9日,结束了成都混团世界杯比赛,@王楚钦___ 、 @孙颖莎 、 @王曼昱 等国乒运动员和教练员等分为三组分别赴成都玉林三巷·民谣里、成都...
Probing the struc- ture of the linker connecting the reductase and heme domains of cytochrome P450BM-3 using site-directed mutagenesis [ J ]. Protein Science, 1996,5 (7) : 1389 - 1393.Govindaraj S,Poulos T L.Probing the structure of the linker connecting the reductase and heme domains ...
1.本外观设计产品的名称:保温瓶(DA1000);2.本外观设计产品的用途:适合于家庭,饭店等用于保温食物;3.本外观设计的设计要点:设计要点在于形状;4.本外观设计产品的后视图与主视图对称,省略后视图;5.最能表明设计要点的图片或者照片:立体图. 陈建平 被引量: 0发表: 2011年 "一月风暴"保温瓶 自从一代文豪巴金老人...
The most abundantly expressed renal UGTs are 1A9 and 2B7, which play a significant role in the glucuronidation of drugs, arachidonic acid, prostaglandins, leukotrienes and P450 derived arachidonic acid metabolites. Modulation by drug substrates (e.g. NSAIDs) of the intrarenal activity of UGT1A9 ...
推进国家治理体系和治理能力现代化,是党的十八届三中全会提出的战略目标.实现乡村治理现代化是国家治理现代化的基础和应有之义.当前在我国乡村治理过程中,存在多元治理主体治理能力软弱和乡村治理主体涣散,各主体之间未能协同合作和良性互动等问题.协同治理模式是现代社会治理的主流模式,也是实现政府治理,农村社会自我调节,...
Cume hydroperoxide impr oxidant for in vitro Cyp2D6 Cyp3A4 P450 turnoverAuclair, K
Son, H.S. Lee, Effect of a new prokinetic agent DA-9701 formulated with corydalis tuber and pharbi- tidis semen on cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes, Evid. Based Complement Altern. (2012) 1-7....