CONSTITUTION: A agent for inhibiting the activity of cytochrome P450 enzyme and NADPH-cytochrome P450 reductase contains cupric ion to inhibit the activity at a protein level. Only the cupric ion of divalent cation metals containing Ca, Cu, Co, Mg, Mn, Zn or the like inhibits a P450 system...
Melatonin and steroid hormones are cytochrome P450 (CYP or P450; EC 1.14.14.1) substrates that have antioxidant properties and mitochondrial protective activities. The mitochondrial intermembrane space (IMS) Cu,Zn-superoxide dismutase (SOD1) is activated after oxidative modification of its critical thiol...
棒头草全P450s分离与表达分析基于棒头草全长转录组基因资源,通过基因功能注释共分离到169个假定的P450基因,根据序列相似性BLAST比对,确定了48个潜在的P450基因.针对不同基因保守区序列设计特异性引物,选用在精噁唑禾草灵胁迫下稳定表达的内参基因集ACT,18S和RUBP进行精确的RT-q PCR分析.为了筛选与棒头草对精噁唑禾...
Probing the struc- ture of the linker connecting the reductase and heme domains of cytochrome P450BM-3 using site-directed mutagenesis [ J ]. Protein Science, 1996,5 (7) : 1389 - 1393.Govindaraj S,Poulos T L.Probing the structure of the linker connecting the reductase and heme domains ...
【#孙颖莎谈国球进校园活动感受#】#孙颖莎说很开心看见小朋友热爱体育# 12月9日,结束了成都混团世界杯比赛,@王楚钦___ 、 @孙颖莎 、 @王曼昱 等国乒运动员和教练员等分为三组分别赴成都玉林三巷·民谣里、成都...
According to the inhibitory potency to Cu 2+, the most sensitive isoenzyme was the EROD in wels, the least was the silver carp's isoenzyme. The investigated fish P450 isoenzymes showed, that the Cu 2+ was a stronger inhibitor than Pb 2+....
本发明公开了一种刮灰结构及随手吸尘器,包括:包括壳体及设于所述壳体中的过滤组件,所述壳体包括:集尘筒,其内部中空且在其端部敞开以形成位于其两端的进气端口与配合端口,所述配合端口112处设置有刮灰结构;挡灰盖,其以可旋转的方式连接至所述集尘筒的进气端口处,以打开和关闭所述进气端口;以及本体,其内部中空且...
推进国家治理体系和治理能力现代化,是党的十八届三中全会提出的战略目标.实现乡村治理现代化是国家治理现代化的基础和应有之义.当前在我国乡村治理过程中,存在多元治理主体治理能力软弱和乡村治理主体涣散,各主体之间未能协同合作和良性互动等问题.协同治理模式是现代社会治理的主流模式,也是实现政府治理,农村社会自我调节,...
Cume hydroperoxide impr oxidant for in vitro Cyp2D6 Cyp3A4 P450 turnoverAuclair, K
P. Morgan. Cytochrome P450: a novel system modulating Ca channels and contraction in mamma- lian heart cells. J. Physiol. (Lond.) 508: 777-792, 1998.Xiao YF,Huang L,Morgan JP.Cytochrome P450:a novel system modulating Ca2+ channels and contraction in mammalian heart cells. Journal of ...