CTSB/CTSDBiomarkerExpressionAutophagySudden cardiac deathOur findings elucidated the expression and regulatory role of cathepsins in coronary heart disease induced SCD and might further explore the potential mechanisms of autophagy in CHD.doi:10.1186/s12872-021-02040-3Dai, Jialin...
2.其次,本发明的活性化合物可以用于治疗和预防增加的自噬流相关疾病,或第三,可以用于抑制组织蛋白酶b(ctsb)、l(ctsl)和/或d(ctsd)和治疗和/或预防组织蛋白酶b(ctsb)、l(ctsl)和/或d(ctsd)相关疾病。3.本发明没有针对任何形式的癌症的治疗。4.纤维化或疤痕形成是一种病理状态,其特征在于胞外基质成分(例如...
Correlation of AGR2 with CTSB and CTSD expression in NPC and LMNPC tissues.Yuejin, LiJinping, LuZhengke, PengGongjun, TanNa, LiuDamao, HuangZhenlin, ZhangChaojun, DuanXiaowei, TangFaqing, Tang
Differential AGR2, CTSB, and CTSD expression among NNET, NPC, and LMNPC tissues.Differential AGR2, CTSB, and CTSD expression among NNET, NPC, and LMNPC tissues.Li, YuejinLu, JinpingPeng, ZhengkeTan, GongjunLiu, NaHuang, DamaoZhang, ZhenlinDuan...
本发明的活性化合物可以用作治疗和/或减轻和/或预防纤维化和/或纤维化相关疾病的药剂,或用作治疗和/或减轻和/或预防自噬和/或自噬相关疾病和抑制自噬流的药剂,和用作抑制组织蛋白酶B(CTSB),L(CTSL)和/或D(CTSD)和/或组织蛋白酶B(CTSB),L(CTSL)和/或D(CTSD)相关疾病的药剂;条件是所述化合物不得用于...
fibrosis and/or related diseases, or for use as a medicament in treating, decreasing the severity and/or progression of and/or preventing autophagy and/or related diseases, for inhibiting autophagy flux, and for inhibiting cathepsins B (CTSB), L (CTSL) and/or D (CTSD) and/or related ...
inhibition of the autophagy flux, or for use in the inhibition of cathepsins B (CTSB), L (CTSL)and/or D (CTSD) and/orcathepsins B (CTSB), L (CTSL) and/or D (CTSD)related diseases; with the proviso that said compounds are not to be used for the treatment of any forms of ...
fibrosis and/or related diseases, or for use as a medicament in treating, decreasing the severity and/or progression of and/or preventing autophagy and/or related diseases, for inhibiting autophagy flux, and for inhibiting cathepsins B (CTSB), L (CTSL) and/or D (CTSD) and/or related ...
Immunohistochemical staining of AGR2, CTSB, and CTSD expressions in normal nasopharyngeal epithelial tissues (NNET), nasopharyngeal carcinoma (NPC), and cervical lymph node metastatic NPC (LMNPC) tissues.Yuejin,...
fibrosis and/or related diseases, or for use as a medicament in treating, decreasing the severity and/or progression of and/or preventing autophagy and/or related diseases, for inhibiting autophagy flux, and for inhibiting cathepsins B (CTSB), L (CTSL) and/or D (CTSD) and/or related ...