Phospho-RNA pol II CTD (Ser2, Ser5) Antibody (PA5-17563) in IHC (P) Immunohistochemistry was performed on paraffin-embedded human lung carcinoma tissue. To expose target proteins, antigen retrieval was performed by boiling tissue sections in 10mM sodium citrate buffer, pH 6.0 fo...
and W.G. Kelly, RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases. Nucleus, 2014. 5(3): p. 224-36.Bowman EA, Kelly WG. RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: a tail of two kinases. Nucleus. ...
[pSer2, pSer5, pSer7]-CTD | MedChemExpress 英文名称: 总访问: 85 国产/进口: 进口 半年访问: 14 产地/品牌: Medchemexpress (MCE) 产品类别: 生化试剂 规格: 1mg 最后更新: 2025-2-13 货号: HY-P1933 CAS 号: 1793080-95-1 参考报价: 询价 立即询价 电话咨询 ...
中文名称:[pSer2, pSer5, pSer7]-CTD CAS号:1793080-95-1 单字母:H2N-Y-pSer-PT-pSer-P-pSer-YSPTSPSYSPTSPS-OH 三字母:H2N -Tyr -Ser(PO3H2) -Pro -Thr -Ser(PO3H2) -Pro -Ser(PO3H2) -Tyr -Ser -Pro -Thr -Ser -Pro -Ser ...
2 . 2 CTD 与 5′→3′间的剪接 mRNA 在转录初期完 成加帽的反应后 , 接下来将进行 转录中期的剪接过程 ,即内含子的剪切去除和外含子的拼接 过程。这一过程需要在剪接体 ( spliceoso me) 的作用指导下完 成 ,而剪接体是一个由核微小核糖核蛋白颗粒 ( SnRN P) 和一 ...
Phosphorylation of RNA polymerase II carboxy-terminal domain (CTD) in hepta-repeats YSPTSPS regulates eukaryotic transcription. Whereas Ser5 is phosphorylated in the initiation phase, Ser2 phosphorylation marks the elongation state. Here we show that the positive transcription elongation factor P-TEFb is...
SCP1 and UBLCP1 contain phosphatase domains similar to FCP1, and also dephosphorylate Ser-2 and Ser-5 of phosphorylated CTD in vitro [13]. The CTDSPL2 gene product contains a CTD phosphatase catalytic domain (CPDc) and the gene is 47% homologous to FCP1. The function of this gene is ...
多种成分包括TFIHp62 和p36 亚基均受 到cdc2/cyelinB 激酶抑制.Gebara 口还发现 CTD 结构是cdc2/cyclinB 激酶的磷酸化底 物.一种可能的模式是,有丝分裂期结合于模 板上的转录延长酶,可因edc2/cyelinB 激酶 抑制TFⅡH 相关激酶等活性,而失去CTD 高磷酸化状态的保持,酶复合体不能与模板 稳定...
Sudhir Kumar Singh1, Mohammad Imran Siddiqi1, Timir Tripathi2 & Md. Sohail Akhtar1 RNA Polymerase II (RNAPII) uniquely possesses an extended carboxy terminal domain (CTD) on its largest subunit, Rpb1, comprising a repetitive Tyr1Ser2Pro3Thr4 Ser5Pro6Ser7 motif with potential ...
Sudhir Kumar Singh1, Mohammad Imran Siddiqi1, Timir Tripathi2 & Md. Sohail Akhtar1 RNA Polymerase II (RNAPII) uniquely possesses an extended carboxy terminal domain (CTD) on its largest subunit, Rpb1, comprising a repetitive Tyr1Ser2Pro3Thr4 Ser5Pro6Ser7 motif with potential ...