Importantly, these results were validated using the Test Set.Conclusions/SignificanceAs the CSF levels of CXCL10, CXCL9, and neopterin were the most strongly correlated with rate of disease progression, they represent the most viable candidates for HAM/TSP prognostic biomarkers. The identification of...
Hagberg L, Cinque P, Gisslen M, et al. Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection. AIDS Res Ther. 2010;3(7):15. Google Scholar Eggers C, Hertogs K, Stürenburg HJ, et al. Delayed central nervous system virus supp...
: W. van Pelt, M.A. Kuiper, P.L.M. Bergmans, T. Teerlink∗, Ph. Scheltens, E.Ch. Wolters. Departments of Neurology and Clinical Chemistry∗, Free university Hospital, P.O. Box 7075, 1007 MB Amsterdam The Netherlands Available online 27 October 2003About ScienceDirect Contact and...
(Hen-ningtest Neopterin; BRAHMS) or enzyme-linked immunosor-bent assay (BRAHMS) with a normal reference value of Neopterin,巨噬细胞活化作用和炎症标志,在CSF和血浆被分析了被一只买得到的放射免疫测定 (母鸡ningtest Neopterin; BRAHMS) 或酵素连接的免疫吸附剂分析用试样 (BRAHMS) 以<8.8 nmol的一个正常...
Neopterin production, tryptophan degradation, and mental depression—what is the link? Brain Behav Immun 2002; 16: 590–595. Article CAS PubMed Google Scholar Muller N, Schwarz MJ . The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression. Mol ...
The relationship of cerebrospinal fluid (CSF) extracellular vesicles (EVs) to neurocognitive impairment (NCI) in HIV-infected individuals is unclear. Here, we characterize CSF EVs and their association with CNS injury-related biomarkers (neurofilament light [NFL], S100B, neopterin) and NCI in HIV+...
CACHEXIA HEMATOLOGICAL NEOPLASIAS NEOPTERIN STNF-R55 TUMOR NECROSIS FACTOR-ALPHA WEIGHT LOSS DOI: 10.1016/0959-8049(93)90623-N 被引量: 8 年份: 1993 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 Elsevier (全网免费下载) Elsevier Semantic Scholar dx.doi.org NCBI 查看更多 ...
Infants with adverse neurodevelopmental outcomes show higher levels of CSF neopterin and β2-microglobulin. The evolution of neopterin levels provides a better predictive capacity than a single determination.Impact Brain inflammation in newborns with HIE could be measurable through the analysis of CSF ...
Methods We measured CSF neopterin, quinolinic acid, kynurenine and kynurenine/tryptophan ratio using a liquid chromatography coupled to tandem mass spectrometry (LC鈥揗S/MS) system. The CSF of 18 children with ITES were compared with acute encephalitis (n=20), and three control groups, namel...
There were statistically significant increases of CSF neopterin, kynurenine, quinolinic acid and kynurenine/tryptophan ratio (KYN/TRP) in the inflammation group compared to all control groups (all p<0.0003). As biomarkers, at thresholds with 95% specificity, CSF neopterin had the best sensitivity ...