CSF drug concentrations greater than or equal to 10 −6 M were achieved in 81% of the courses. The highest level was 8.4 × 10 −6 M. Only 5% of patients failed to achieve this drug concentration in at least one cycle. No significant correlation was observed between blood and CSF ...
Recommend dissolved to store concentration with sterile water (or PBS), add 200ml water to reach the concentration at 250μl/ml is a good idea. Dilution: Proposal to diluted withCellGenix®Serum free Media. And please add carrier protein when diluted with sterilewater or PBS, wich prevent ...
The concentration of NVP-BEP800 which inhibits Hsp90β by 50% is determined from the competition curve. 别名 PLX-3397 化学信息 分子量 417.81 分子式 C20H15ClF3N5 CAS No. 1029044-16-3 Smiles FC(F)(F)c1ccc(CNc2ccc(Cc3c[nH]c4ncc(Cl)cc34)cn2)cn1 密度 1.458 g/cm3 (Predicted) 储存&...
PLX5622 是一种 CSF1R 抑制剂 (IC50=0.016 µM),具体选择性、口服活性和血脑屏障通透性。PLX5622 可以引起持续和特异性的小胶质细胞的消除。 规格价格库存数量 1 mg¥ 428现货 5 mg¥ 977现货 10 mg¥ 1,633现货 25 mg¥ 2,747现货
Protein solutions are generally not very stable when frozen at low concentration. Upon freeze and thaw, some proteins in the solution may stick to the wall of the container, which results in significant reduction of protein concentration if the starting concentration was low. Therefore, carrier prot...
zero to infinity;CL/F,apparent serum clearance after SC administration of dose;MRT,Mean residence time; Tc<2ng/ml,time of plasma concentration less than 2ng/ml which supposed to be as the lowest drug effective concentration.The Tc<2ng/ml for the dose 12.5μg/kg of PEG30-rhG-CSF is ...
Fox E, Bungay PM, Bacher J, et al. Zidovudine concentration in brain extracellular fluid measured by microdialysis: steady-state and transient results in rhesus monkey. J Pharmacol Exp Ther. 2002;301(3):1003–11. PubMedCAS Thomas SA, Segal MB. The transport of the anti-HIV drug, 2′,3...
Capillary Leak Syndrome: Has been reported after G-CSF administration, including pegfilgrastim products, and is characterized by hypotension, hypoalbuminemia, edema, and hemoconcentration. Episodes vary in frequency, severity and may be life-threatening if treatment is delayed. If symptoms develop, ...
After the first urine specimens, representing concentrated and acidified visible components (such as blood cells, epithelial cells, tubular) easy to observe the relative concentration. Random urine that is a random urine specimens convenient, but by diet, Sports, and even more the influence of dr...
FC The suggested concentration for this CSF-1R antibody (clone AFS98) antibody for staining cells in flow cytometry is ≤ 0.25 μg per 106 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application. Additional Applications Reported In Lit...