Crypt cell proliferation and HLA-DR expression in pelvic ileal pouches. J Clin Pathol. 1990 Oct; 43 (10):824–828.de Silva HJ, Gatter KC, Millard PR, Kettlewell M, Mortensen NJ, Jewell DP. Crypt cell proliferation and HLA-DR expression in pelvic ileal pouches. J Clin Pathol 1990;43:...
After 18 hours a stathmokinetic technique was used to determine the crypt cell proliferation rate (CCPR) by adding vincristine sulphate (1渭/ml) to the culture medium. Tissue samples were removed at hourly intervals for A hours and the mean number of metaphase arrests in 10 whole crypts was...
1,25(OH)2D3 INHIBITS CRYPT CELL PROLIFERATION INHUMAN COLORECTAL MUCOSA. Thomas M G, Tebbut S and Williamson R C N. Department of Surgery, Royal Postgraduate Medical School, London. U.K Introduction Vitamin D (1,25 (OH)2D3) has been shown to induce differentiation and inhibit cellular p...
proliferation. In addition, this complex responds to R-spondin growth factors secreted bycrypt cellsto further enhance the proliferation of CBCs. Addition of exogenous Wnt3A to cultured organoids causes them to transform into rounded cysts lacking any differentiated cell types, and inhibition of Wnt ...
Previously we showed that Rack1 (Receptor for Activated C Kinase) regulates growth of colon cells in vitro , partly by suppressing Src kinase activity at key cell cycle checkpoints, in apoptotic and cell survival pathways and at cell-cell adhesions. Here, we generated mouse models of Rack1 de...
b, Influence of crypt size φ and shape factor \(\tilde \kappa _0\) on critical values of m (with vev = 1, that is no cell swelling) and vev (with m = 2, that is constant crypt apical tension) for organoid budding. c-e, Influence of preferential proliferation of crypt ...
The signals of Ki-67-positive cells was enhanced in the crypts as visualized by multiphoton fluorescence microscopy, whereas the TUNEL-positive cells were decreased in the villi of HSD, suggesting greater crypt cell proliferation and a reduction of villous cell apoptosis. ...
Wnts and R-spondins (RSPOs) support intestinal homeostasis by regulating crypt cell proliferation and differentiation. Ex vivo, Wnts secreted by Paneth cells in organoids can regulate the proliferation and differentiation of Lgr5-expressing intestinal stem cells. However, in vivo, Paneth cell and ...
These cells express mouse telomerase reverse transcriptase (mTert), which is thought to regulate stem cell proliferation and mobilization, a hypothesis supported by its common expression in rapidly dividing cells such as the bone marrow and testis, in addition to the intestine [41]. Consistent with...
Cell proliferation at different sites along the length of the rat colon. Virchows Arch B Cell ... JP Sunter,AJ Watson,NA Wright,... - 《Virchows Archiv B Cell Pathology》 被引量: 111发表: 1980年 Cellular proliferation in proximal and distal rat colon during 1,2-dimethylhydrazine-induced ...