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HRYZ-T101产品是恒瑞源正针对实体瘤创新靶点的First-in-class TCR-T细胞治疗产品,基于反向基因工程的TCR筛选技术平台ReGET,可以从免疫治疗获益的肿瘤患者体内快速高效地分离最优亲和力的TCR,积累了大量基于亚洲人群HLA分型的TCR数据,用于抗肿瘤TCR-T产品研发,与基于欧美人...
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最终,有30名患者入选,中位年龄65岁(IQR 57-70岁),70%为男性。其中的50%使用HeartMate II,33% HeartMate 3,17%则使用HeartWare HVAD,LVAD支持的中位时间为309天(IQR 101-631天)。 图3 入选30名患者的基线指标 随机分配的结果,19名患者首先接受了BiV起搏(平均起搏百分比95%),11名患者则接受了RV起搏(平均...