There are some well-known signaling and transcription factor genes with a high degree in the GPCM, such as EGFR, AKT, MYC, and p53 (Additional file 1: Table S4). The gene with the highest degree in the network is GNB1, a subunit of G proteins, which are modulators or transducers in...
Because of this, it has also not been possible to study how variation in gene transcription of plant genes is related to variation in gene transcription of the AMF partner. In this study, we aimed to understand the contribution of intra-specific genetic variation of a host plant and an AMF...
It is important to note that the vertical axes shown in Figure 2 only represent normalized expression changes relative to the control. Absolute values displayed on these axes, including negative values, have no real meaning, and only differences relative to control are taken into account. This ...
The crosstalk between ET, JA, and ABA in the regulation of germination was studied by comparing the transcription levels of different genes involved in the biosynthesis and signaling pathways of ABA, JA, and ET in the seeds of the WT, aco1a, and lox3a germinated under both water and salt ...
However, there is a difference in one of them, that is, 𝑚2m2 contains an additional transition 𝑡63t63, which does not change the overall biological meaning of this MCT set. Obviously, the MCT set containing virus-independent transitions cannot be determined for t-invariants solely ...
In association with the lymphocyte biomarkers, we first noticed a significant decrease in Cd4 in both situations and a parallel tendency of an increase in Cd8a in G3/G2 (Figure 4 and Figure 5, top left), meaning a dramatic decrease in the Cd4 to Cd8a ratio. Among all the proteins ...
In M. oryzae, the ratio of NAD+/NADH in the ΔMomcs1 aerial mycelium decreased, and the content of nitric oxide (NO) also decreased, meaning that the methylcitrate cycle is involved in the cellular redox state and NO signaling [13]. The altered NAD+/NADH ratio may be related to the ...
Interestingly, collagen type I accumulates ROS-scavenging residues (Tyr/Phe/Met) to prevent mechano-oxidative damage to the tissue, meaning that mechanical stress on collagen leads to ROS production [55]. Under chronic stress conditions, the endoplasmic reticulum (ER) accumulates reactive oxygen ...
The importance and meaning of this interaction need to be further analyzed in vivo, given the fact that PPAR is considered a tumor suppressor gene and clinical trials using PPAR-agonists in the treatment of cancer are in course [85]. The activity of EGFR can be modulated by post-...