Conclusions These results suggest that the chloroplast-targeted CFM4, one of two Arabidopsis genes encoding a single CRM domain-containing protein, harbors RNA chaperone activity and plays a role in the Arabidopsis growth and stress response by affecting rRNA processing in chloroplasts.Kwanuk Lee...
Here, we provide a comprehensive table for the validated cargo proteins, containing the location of the NES consensus patterns with the disordered propensity plots, known protein domain information, and the predicted secondary structures. It could be useful for determining the most plausible NES region...
CLD, cyclophilin-like domain; IR, internal repeat region of RanBP2 containing its SUMO E3 ligase actvity. Vertical dashes denotes FG-repeats. Full size image RanBP2’s interaction with RanGAP1 depends on post-translational modification of the C-terminal tail domain of RanGAP1 with the ubiquitin...
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 来源: Polyclonal, Rabbit,IgG 稀释: WB 1:1000-2000 ELISA 1:5000-20000 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. 浓度: 1 mg/ml...
Within the domain, the serine 139 can be phosphorylated by members of the phospholipid inositol-3 kinase family including ataxia-telangiectasia-mutated (ATM), ATM and Rad3-Related (ATR), and DNA-dependent protein kinases (DNA-PKS) [39, 40]. Both in vivo and in vitro studies have shown ...
The splicing of all but one of the subgroup IIB introns requires a heterodimer containing the peptidyl-tRNA hydrolase homolog CRS2 and one of two closely related proteins, CAF1 or CAF2, that harbor a recently recognized RNA binding domain called the CRM domain. Two CRS2/CAF-dependent introns ...
An RNPS1 (RNA-binding protein S1, serine-rich domain) cDNA was isolated by yeast three-hybrid screening, using bait containing two CSS regions. We showed that RNPS1 might recognize IFN-α1 mRNP that includes CRM1. The data demonstrate that interaction between RNA structures in the coding ...
Sub1/PC4 a chromatin associated protein with multiple functions in transcription Yeast Sub1 and its human ortholog PC4 display multiple cellular functions in vivo. Sub1/PC4 contains a unique conserved non-specific DNA-binding domain and... Christine,Conesa,Joël,... - 《Rna Biology》 被引量:...
A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway Cell, 83 (1995), pp. 415-422 Google Scholar 40 W.M. Michael, P.S. Eder, G. Dreyfuss The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the...
An Intrabody Based on a Llama Single-domain Antibody Targeting the N-terminal α-Helical Multimerization Domain of HIV-1 Rev Prevents Viral Production. The human immunodeficiency virus, type 1 (HIV-1)-encoded Rev protein is essential for the expression of late viral mRNAs. Rev forms a large...