9 月 3 日，由 18 位来自多国科研机构的成员组成的“人类生殖系基因组编辑临床应用国际委员会” （International Commission on the Clinical Use of Human Germline）发布报告，称基因编辑技术 CRISPR 不能满足有效和可靠地对人类胚胎完成精确基因编辑的条件，也无法完全避免不可预计的编辑失误；在未能达到这一标准...
I'm excited to tell you about a new kind of collaboration that will absolutely create solutions to these big problems. It's a collaboration that's unexpected because it's between humans and the tiniest organisms that populate our planet: the bacteria ...
The lived experience of stakeholders involved in using CRISPR in humans sets the foundation for how we should think about its future applications. This chapter discusses the importance of centering an anticipatory ethical analysis on the philosophical phenomenology and postphenomenology. Both of these ...
Should we edit a human embryo? And my personal favorite: How can we justify wiping out an entire species that we consider harmful to humans off the face of the Earth, using this technology? 有人听说过CRISPR(一种基因编辑技术)吗?大家应该都知道吧。这是一种人为改变染色体的技术。这种技术如此全...
The significant leap in gene-editing tools brought new urgency to long-standing discussions about theethicaland socialimplicationssurrounding thegenetic engineeringof humans. Many questions, such as whether genetic engineering should be used to treathuman diseaseor to alter traits such as beauty or intel...
(CRISPR People: The Science and Ethics of Editing Humans) 作者:Henry T. Greely 出版社:MIT Press(2021) 《破译者:Jennifer Doudna、基因编辑与人类的未来》 (The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race) ...
For therapeutic application in humans, such designer nucleases should recognize various HBV genotypes and cause minimal off-target effects. Here, we identified cross-genotype conserved HBV sequences in the S and X region of the HBV genome that were targeted for specific and effective cleavage by a...
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How Can CRISPR-Cas9 Help Humans? CRISPR Treatment is very effective in gene editing. CRISPR-Cas9 has been proven to benefit human beings in treating major genetic defects. The protein CAS9 Acts as a molecular scissor that can cut the defected DNA strands (Crawford, 2017). Gene editing has be...
In this review, we will focus on the latest advancements in the development of disease model in rodents. Because of their phylogenetic relatedness and physiological similarity to humans, their maintenance facility, and easy breeding in the laboratory, mice and rats are the most widely used ...