Creutzfeldt–Jakob disease (CJD) is the most common human prion disease1. CJD is categorized into four different types: variant (vCJD), sporadic (sCJD), familial, and iatrogenic2. While the disease first received the public
Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common form of prion diseases. The causes of sCJD are still unknown and exogenous factors may play a role. Worldwide, the number of patients with sCJD has progressively increased over time. This increase can be partly explained by increasing...
The disease's main presentation includes rapidly progressive dementia, with behavioral abnormalities, gait ataxia, extrapyramidal features, and eventually, myoclonus. Life expectancy following diagnosis is usually six months to one year [6]. CJD's definitive diagnosis is performed through histopatholo...
LIFE EXPECTANCYISCHEMIC HEART DISEASECreutzfeldt-Jakob disease (CJD) is a transmissible neurodegenerative disorder characterized by the accumulation of the amyloid protein PrP in the CNS. Two coding polymorphisms of the PrP gene (PRNP) are a methionine (Met) to valine (Val) change at codon 129, ...