Crestor May Be Safer Than Other Statins, FDA Tells Public CitizenLee Kalowski
*At 20-mg dose vs 7% with placebo.See how CRESTOR compared to 2 other statins In the ECLIPSE clinical trial CRESTOR lowered bad (LDL) cholesterol in high-risk patients[†a] more than Lipitor® (atorvastatin calcium) About the ECLIPSE Trial: ECLIPSE was a 24-week clinical trial involving...
996 controls did not find a significantteratogeniceffect from maternal use of statins in the first trimester of pregnancy, after adjusting for potential confounders – includingmaternal age,diabetesmellitus,hypertension,obesity, and alcohol and tobacco use – using propensity score-based method...
Adverse Events(AE) reported in CRESTOR 40 mg vs Placebo 10 mg Adverse ReactionsCRESTOR 40 mg N=700Placebo 10 mg N=281 Myalagia 12.7 12.1 Arthralgia 10.1 7.1 Headache 6.4 5.3 Dizziness 4.0 2.8 Increased CPK 2.6 0.7 Abdominal pain 2.4 1.8 [†]ALT>3x ULN 2.2 0.7 Adverse Events(AE) repor...
information on the effects of the drug on the breastfed infant or the effects of the drug on milk production. Statins, including CRESTOR, decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol and may cause harm to the breastfed ...
ATP III LDL-C goal attainment by dose at 6 weeks in patients with hyperlipidemia or mixed dyslipidemia treated with CRESTOR vs other statins[5a] For a 10 mg dose, 82% of 473 rosuvastatin patients[†], 69% of 633 atorvastatin patients, 51% of 648 simvastatin patients, and 31% of 485 ...
information on the effects of the drug on the breastfed infant or the effects of the drug on milk production. Statins, including CRESTOR, decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol and may cause harm to the breastfed ...