We report the case of a 70-year-old woman with CREST syndrome and vasculitis who developed multifocal symptomatic bronchiectasis. The bronchiectasis and immunosuppressive therapy precipitated severe lower respiratory tract infection, which was fatal within a few months. The concomitant occurrence of ...
CREST Syndrome Figs. 16.67and16.68 CREST syndromeis an uncommon condition that is related to systemic sclerosis, and some investigators feel that this is a form of limited cutaneous systemic sclerosis. The acronym stands forCalcinosis cutis,Raynaud phenomenon,Esophageal dysfunction,Sclerodactyly, andTelang...
The antibody was not detected in the serums of patients with rheumatoid arthritis, Sjo篓rgren's sicca complex or linear scleroderma. Patients with osteoarthritis who were age- and sex-matched to the group with the CREST syndrome did not have anti-centromere antibodies. Autoantibodies found in ...
A 69-YEAR-OLD WOMAN WITH LUPUS-ERYTHEMATOSUS AND PAINFUL SKIN-LESIONS OF THE FEET - MULTIPLE-MYELOMA, WITH IGG-KAPPA SERUM-M COMPONENT - CRYOGLOBULINEMIA, TYPE-I - (OVERLAP SYNDROME OF CALCINOSIS, RAYNAUDS-PHENOMENON, ESOPHAGEAL DYSMOTILITY, SCLERODACTYL, AND TELANGIECTASIA [CREST] AND SYSTEMIC ...
Ocular manifestations of antiphospholipid (Hughes)' syndrome--minor features? The ocular manifestations are described in autoimmune disease, being most common associated with systemic lupus erythematosus, scleroderma, rheumatoid arthritis, insulin-dependent diabetes mellitus, and dermatomyositis. Nonetheless, the...
et al. PHOX2B genotype allows for prediction of tumor risk in congenital central hypoventilation syndrome. American journal of human genetics. 2005;76(3):421-426 14. Southard-Smith EM, Kos L, Pavan WJ. Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nature...
CREST syndromerheumatoid arthritiBackground: Systemic sclerosis is a disease characterized by sclerosis of the skin, internal organs and vasculopathy. Articular manifestations are common, and include arthralgias, arthritis, and morning stiffness, which in some cases can be confused with rheumatoid ...
syndromeBackground: Systemic sclerosis is a disease characterized by sclerosis of the skin, internal organs and vasculopathy. Articular manifestations are common, and include arthralgias, arthritis, and morning stiffness, which in some cases can be confused with rheumatoid arthritis (RA). Patients ...
Sjögren syndrome, or isolated Raynaud phenomenon; and rarely with rheumatoid arthritis, systemic lupus erythematosus, and other connective tissue diseases. Other ANAs (e.g., anti-ssDNA, anti-RNP) occasionally may be present.365Elevated levels of soluble CD31 were reported in patients with a relat...