Although albuminuria has been linked to heart failure in the general population, the relationship between urine albumin-to-creatinine ratio (uACR) and heart failure in type 2 diabetes patients is not well understood. We aimed to investigate the relationship between uACR and new-onset heart failure ...
kidney function testBackground. A creatinine clearance (CrCl) is still often requested to estimate the glomerular filtration rate (GFR) in clinical practice. However, the diversity of serum and urine creatinine (Scr, Ucr) assays leads to different CrCl-results which are here compared with each ...
The pH of the urine can affect the secretion, reabsorption, and overall excretion of ionized compounds; an acidic pH promotes excretion of weak bases, while an alkaline pH will promote excretion of weak bases. If there is no secretion or reabsorption, Eq. (16) simplifies to Clrkidney = fd...
An elevated urine albumin creatinine ratio (UACR) is a marker of renal dysfunction and an independent predictor of cardiovascular disease1,2. In addition, several studies have shown that moderately increased albuminuria (UACR < 30 mg/g) within the accepted normal range is associated with highe...
The results from group 2, using fresh urine samples examined without delay, confirmed this relationship (Fig 6) as did the correlation of urinary ammonium to standard bicarbonate and creatinine clearance (Fig 4). The small elevation of blood pH (within the normal range) observed in the patients...
However, if spot urine P/C ratio is >20 mg/mmol (0.2 mg/mg), or >50 mg/mmol (0.5 mg/mg) for children under 2 years of age, or the urine test results are abnormal (e.g. hema- turia, leukocyturia, active urinary sediment), persistent proteinuria or proteinuria of clinical ...
Since serum creatinine is highly correlated with 24-h urine excretion (r = 0.82, p < 0.0001) in subjects with normal renal function [9], it may represent an acceptable and easily measured surrogate marker of muscle mass. Low serum creatinine levels were associated with a higher risk of T2DM...
The mean value of the serum creatinine concentration measured at the beginning and at the end of the urine collection period was used for ECC calculations.15 Key Secondary End Point Requirement for renal replacement therapy (RRT) was the main related clinical parameter. Sites were advised to ...
, and model 3 was additionally adjusted for presence of RKF defined as daily urine volume > 200 mL/day.Pfor trend test was conducted by including the nutritional indexes quartiles as an ordinal score to the regression models. We evaluated the discriminative ability of each model using ...
Also, cystatin C is a nonglycosylated 13 kDa basic protein that is filtered by the glomeruli and reabsorbed and catabolized by the tubular epithelial cells, with only small amounts excreted in the urine (2). Because of its freely filter- able size through the glomerular filtration barrier, ...